Boc-Val-OH
N-(tert-Butoxycarbonyl)-L-valine (CAS: 13734-41-3), also known as Boc-Val-OH, is a derivative of the amino acid L-valine with a tert-butyloxycarbonyl (Boc) protecting group. It is a white crystalline solid with a molecular weight of 217.26 g/mol. This compound is widely utilised in peptide synthesis and as a chiral building block in organic chemistry, serving as a valuable reagent for researchers and manufacturers.
- IUPAC
- (S)-2-(Boc-amino)-3-methylbutyric acid,N-(tert-Butoxycarbonyl)-L-valine,Boc-L-valine
- Synonyms
- N-(tert-Butoxycarbonyl)-L-valineBoc-L-valine(S)-2-(Boc-amino)-3-methylbutyric acid

Peptide Synthesis
N-(tert-Butoxycarbonyl)-L-valine is a crucial protected amino acid used in the solid-phase and solution-phase synthesis of peptides. The Boc group facilitates controlled chain elongation by preventing unwanted reactions at the N-terminus during coupling steps.
Chiral Building Block
As a chiral molecule, Boc-Val-OH serves as a valuable synthon in the asymmetric synthesis of complex organic molecules. Its stereochemistry can be precisely transferred to target compounds in pharmaceutical and agrochemical research.
Organic Synthesis
This compound finds application as a reagent in various organic transformations where a protected valine moiety is required. It can be used in the development of new synthetic methodologies and the creation of novel chemical entities.
| Molecular weight | 217.26 |
|---|---|
| Linear formula | (CH3)2CHCH(COOH)NHCOOC(CH3)3 |
| Assay | ≥99.0% (T) |
| Optical activity | [α]20/D −6.2±0.5°, c = 1% in acetic acid |
| Melting point | 77-80 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Val-OH used for?
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Boc-Val-OH is primarily used in peptide synthesis as a protected amino acid and as a chiral building block in asymmetric organic synthesis.
What is the CAS number and molecular formula for Boc-Val-OH?
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The CAS number for Boc-Val-OH is 13734-41-3. Its linear formula is (CH3)2CHCH(COOH)NHCOOC(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Val-OH with an assay of ≥99.0% (T). This product is not represented as USP, BP, or EP grade.
What are the safety and handling precautions for Boc-Val-OH?
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When handling Boc-Val-OH, it is essential to wear safety measures including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended for respiratory protection. The substance is classified under WGK Germany 3.
Is Boc-Val-OH a controlled substance?
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The provided data does not indicate that Boc-Val-OH is a controlled substance.
How is Boc-Val-OH packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter since 1998, ensures appropriate packaging and adherence to regulations for the safe and efficient shipping and export of chemical products like Boc-Val-OH.
How can I request a quote or sample of Boc-Val-OH?
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Please contact our sales team directly to request a quote or a sample of Boc-Val-OH. Our team will be pleased to assist you with your specific requirements.
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