2-(Diphenylphosphino)-N,N-dimethylbenzylamine
2-(Diphenylphosphino)-N,N-dimethylbenzylamine (CAS 53881-33-7) is a phosphine ligand with a molecular weight of 319.38 g/mol. This compound is primarily utilised as a ligand in various cross-coupling reactions, facilitating the formation of carbon-carbon and carbon-heteroatom bonds in organic synthesis. Its structure, featuring a diphenylphosphino group and a dimethylamino group on a benzyl core, offers unique electronic and steric properties beneficial for catalytic applications.
- IUPAC
- (2-((Dimethylamino)methyl)phenyl)diphenylphosphine
- Synonyms
- C21H22NP(2-((Dimethylamino)methyl)phenyl)diphenylphosphine
Catalysis in Cross-Coupling Reactions
This phosphine ligand is employed in transition metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Buchwald-Hartwig, and Heck couplings. It assists in stabilising catalytic intermediates and promoting efficient bond formation.
Ligand for Organic Synthesis
The compound serves as a versatile ligand in complex organic synthesis, enabling chemists to construct intricate molecular architectures. Its application is key in the development of new pharmaceuticals and advanced materials.
Phosphine Chemistry Research
As a representative of phosphine compounds, it is valuable in research settings for studying the behaviour and reactivity of organophosphorus compounds in catalysis and coordination chemistry.
| Molecular weight | 319.38 |
|---|---|
| Empirical formula | C21H22NP |
| Assay | 95% |
| Application | Phosphine ligand for cross coupling |
| Melting point | 55-59 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Ligand For | Cross Couplings |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Diphenylphosphino)-N,N-dimethylbenzylamine used for?
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2-(Diphenylphosphino)-N,N-dimethylbenzylamine is primarily used as a phosphine ligand in cross-coupling reactions for organic synthesis and catalysis.
What is the CAS number and molecular formula for 2-(Diphenylphosphino)-N,N-dimethylbenzylamine?
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The CAS number is 53881-33-7 and the empirical formula is C21H22NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Diphenylphosphino)-N,N-dimethylbenzylamine with an assay of 95%. This product is supplied for research and laboratory use and is not represented as USP, BP, or EP grade.
How should 2-(Diphenylphosphino)-N,N-dimethylbenzylamine be handled safely?
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This compound is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including gloves, eye protection, and ensure adequate ventilation. Avoid breathing dust/fume/gas/mist/vapours/spray. In case of eye contact, rinse cautiously with water for several minutes and seek medical advice.
Is 2-(Diphenylphosphino)-N,N-dimethylbenzylamine available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-(Diphenylphosphino)-N,N-dimethylbenzylamine.
How can I request a sample or quote for this chemical?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
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