2-(4,5-Dihydro-2-oxazolyl)quinoline
2-(4,5-Dihydro-2-oxazolyl)quinoline (CAS: 202191-126) is a heterocyclic organic compound with the molecular formula C12H10N2O and a molecular weight of 198.22 g/mol. It functions as a nitrogen-donor ligand, particularly useful in catalysis and chemical synthesis. Its structure lends itself to applications in cross-coupling reactions and as a building block for more complex molecules in various research and development settings.
- IUPAC
- 2-(2-Quinolinyl)oxazoline,Sigman ligand
- Synonyms
- 2-(2-Quinolinyl)oxazolineSigman ligand

Catalysis and Cross-Coupling Reactions
This compound serves as a valuable nitrogen-donor ligand in catalytic systems. It is particularly noted for its utility in facilitating various cross-coupling reactions, enabling the formation of carbon-carbon and carbon-heteroatom bonds.
Chemical Synthesis Intermediate
As a quinox ligand derivative, 2-(4,5-Dihydro-2-oxazolyl)quinoline is employed as a key intermediate in the synthesis of diverse organic molecules. Its unique structure can be incorporated into larger molecular frameworks for fine chemical and pharmaceutical research.
Ligand Design and Coordination Chemistry
The compound's structure, featuring both quinoline and oxazoline moieties, makes it of interest in coordination chemistry. It can coordinate with various metal centres, forming complexes with potential applications in materials science and homogeneous catalysis.
| Molecular weight | 198.22 |
|---|---|
| Empirical formula | C12H10N2O |
| Assay | ≥96.5% (HPLC)97% |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Hazard codes (EU) | Xi |
|---|---|
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(4,5-Dihydro-2-oxazolyl)quinoline primarily used for?
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2-(4,5-Dihydro-2-oxazolyl)quinoline is primarily used as a nitrogen-donor ligand in catalysis, particularly for cross-coupling reactions, and as an intermediate in chemical synthesis.
What is the CAS number and molecular formula for this compound?
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The CAS number is 202191-126, and the molecular formula is C12H10N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a purity of ≥96.5% (HPLC) or 97%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 2-(4,5-Dihydro-2-oxazolyl)quinoline be handled?
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This compound is classified as a Warning. It causes skin irritation (H315) and serious eye irritation (H319). Always handle in a well-ventilated area, wear appropriate protective gloves and eye protection, and avoid breathing dust/fume/gas/mist/vapours/spray. In case of eye contact, rinse cautiously with water for several minutes (P305 + P351 + P338).
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring compliant and secure packaging and shipping procedures for international destinations.
How can I request a sample or a quote?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team via the website or direct inquiry channels, providing your specific requirements.
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