(1,5-Cyclooctadiene)(methoxy)iridium(I) dimer

CAS 12148-71-9[Ir(OCH3)(C8H12)]2Catalysis & Inorganic

(1,5-Cyclooctadiene)(methoxy)iridium(I) dimer (CAS 12148-71-9) is a valuable organometallic compound with a molecular weight of 662.86. It serves as a highly effective catalyst in various organic synthesis applications, particularly in C-H activation and cross-coupling reactions. Its utility extends to the preparation of complex heterocyclic systems and asymmetric synthesis, making it a key reagent for advanced chemical research and development.

IUPAC: Bis(1,5-cyclooctadiene)di-μ-methoxydiiridium(I),[Ir(OMe)(1,5-cod)]2
Synonyms: [Ir(OCH3)(C8H12)]2Bis(1,5-cyclooctadiene)di-μ-methoxydiiridium(I)[Ir(OMe)(1,5-cod)]2

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(1,5-Cyclooctadiene)(methoxy)iridium(I) dimer ([Ir(OCH3)(C8H12)]2) — chemical structure, CAS 12148-71-9; Chemistry, fine chemical supplied by Tech Serve Solutions

C-H ActivationCatalystsChemical SynthesisIridium

01 /Applications

C-H Activation and Functionalisation

This iridium dimer is a potent catalyst for C-H activation reactions, enabling the ortho-silylation of aromatic ketones, benzaldehydes, and benzyl alcohols. It facilitates direct functionalisation of otherwise inert C-H bonds.

Cross-Coupling Reactions

It catalyses Suzuki-Miyau<wbr>ra coupling reactions and metalation-Suzuki cross-coupling procedures, essential for the synthesis of biaryl and heterobiaryl compounds. Tetraborylation reactions are also efficiently promoted.

Heterocyclic Synthesis

The compound has been employed in the preparation of heteroaryl fused indole ring systems. These derivatives have shown potential as inhibitors of the HCV NS5B polymerase.

Asymmetric Hydroboration

It is utilised in highly regio- and enantioselective asymmetric hydroboration reactions, providing a stereocontrolled route to valuable chiral boronic acid derivatives.

02 /Properties

Molecular weight	662.86
Linear formula	[Ir(OCH3)(C8H12)]2
Application	Catalyst for:• Preparation of heteroaryl fused indole ring systems as inhibitors of HCV NS5B polymerase1• Borylation/Suzuki-Miyaura coupling2• Metalation-Suzuki cross-coupling procedure for the synthesis of biaryls and heterobiaryls3• Tetraborylation reactions4• Highly regio- and enantioselective asymmetric hydroboration5• Ortho-silylation of aryl ketone, benzaldehyde, and benzyl alcohol derivatives via C-H activation6
Melting point	154-179 °C (D)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

12148-71-9

MDL number

MFCD08459360

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (1,5-Cyclooctadiene)(methoxy)iridium(I) dimer used for?

This iridium dimer is a catalyst used in various organic synthesis applications, including C-H activation, cross-coupling reactions such as Suzuki-Miyau<wbr>ra coupling, the synthesis of heterocyclic compounds, and asymmetric hydroboration.

What is the CAS number and formula for (1,5-Cyclooctadiene)(methoxy)iridium(I) dimer?

The CAS number is 12148-71-9. The linear formula is [Ir(OCH3)(C8H12)]2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical for research and development purposes. The exact grade and purity are available on the Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should (1,5-Cyclooctadiene)(methoxy)iridium(I) dimer be handled?

This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a P2-type dust mask. Ensure good ventilation. Store in a dry place.

How is this product packed, shipped, and exported?

Products are carefully packed according to international shipping regulations. Tech Serve Solutions is a global exporter and can facilitate shipment to most international destinations.