XPhos Pd G3
XPhos Pd G3 (CAS: 1445085-55-1) is a third-generation palladacycle catalyst, identified by its empirical formula C46H62NO3PPdS and a molecular weight of 846.45 g/mol. This homogeneous palladium catalyst is a valuable tool in organic synthesis, particularly for facilitating challenging cross-coupling reactions. Its design offers enhanced activity and broader substrate scope compared to earlier generations, making it a key reagent for modern synthetic chemistry.
- IUPAC
- (2-Dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II) methanesulfonate,XPhos-G3-Palladacycle,XPhos-Pd-G3
Cross-Coupling Reactions
XPhos Pd G3 is highly effective in mediating various palladium-catalyzed cross-coupling reactions, including Suzuki-Miyaura, Buchwald-Hartwig amination, and Negishi couplings. Its advanced ligand structure promotes efficient bond formation between diverse organic fragments.
Catalysis in Organic Synthesis
As a sophisticated organometallic catalyst, it plays a crucial role in constructing complex molecular architectures. It enables chemists to synthesize pharmaceutical intermediates and fine chemicals with improved yields and selectivities.
Buchwald Ligand Systems
Belonging to the esteemed family of Buchwald's third-generation palladacycles, XPhos Pd G3 represents a significant advancement in catalyst design. It offers solutions for sterically hindered substrates and challenging coupling partners.
| Molecular weight | 846.45 |
|---|---|
| Empirical formula | C46H62NO3PPdS |
| Assay | 95% |
| Impurities tested | ≤6%(acetone)≤6%(pentane) |
| Melting point | 146-151 °C (decomposition) |
Hazard statements
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Risk statements (R) | 52/53 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is XPhos Pd G3 used for?
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XPhos Pd G3 is primarily used as a catalyst in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig aminations, for organic synthesis.
What is the CAS number and formula for XPhos Pd G3?
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The CAS number for XPhos Pd G3 is 1445085-55-1. Its empirical formula is C46H62NO3PPdS.
What grade and purity does Tech Serve Solutions supply for XPhos Pd G3?
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Tech Serve Solutions supplies XPhos Pd G3 with an assay of 95%. This product is not classified as USP, BP, or EP grade; TSS does not represent it as such.
What are the safety and handling recommendations for XPhos Pd G3?
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XPhos Pd G3 is classified with hazard statement H412 (Harmful to aquatic life with long lasting effects). Precautionary statement P273 (Avoid release to the environment) should be followed. Handle with appropriate personal protective equipment in a well-ventilated area.
How is XPhos Pd G3 packed and shipped?
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XPhos Pd G3 is carefully packed to ensure stability during transit and is exported globally by TSS. Specific packing details are available upon request.
How can I request a quote or sample for XPhos Pd G3?
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To request a quote or sample of XPhos Pd G3, please contact our sales team through the website or by phone, referencing the CAS number 1445085-55-1.
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