XPhos Pd G2
XPhos Pd G2 (CAS: 1310584-14-5) is a second-generation Buchwald palladacycle complex with a molecular weight of 786.80 g/mol. This homogeneous palladium catalyst is highly effective in facilitating Suzuki-Miyaura cross-coupling reactions, a fundamental transformation in organic synthesis. It is widely employed in academic and industrial research for the construction of complex molecules, particularly in the pharmaceutical and fine chemical sectors.
- IUPAC
- 2nd Generation XPhos Precatalyst,Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II),X-Phos aminobiphenyl palladium chloride precatalyst,XPhos-Pd-G2
- Synonyms
- XPhos-Pd-G2X-Phos aminobiphenyl palladium chloride precatalyst2nd Generation XPhos PrecatalystChloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II)
Suzuki-Miyaura Cross-Coupling
XPhos Pd G2 is a key catalyst for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds. It is effective with a wide range of substrates, facilitating the synthesis of biaryl compounds and other complex organic structures.
Buchwald Precatalyst
As a second-generation Buchwald precatalyst, it offers improved activity and stability compared to earlier generations. This makes it suitable for demanding cross-coupling applications in chemical synthesis.
Homogeneous Palladium Catalysis
This complex serves as a versatile homogeneous palladium catalyst in various organic transformations. Its design allows for efficient catalytic cycles in solution, aiding in the synthesis of diverse chemical entities.
| Molecular weight | 786.80 |
|---|---|
| Empirical formula | C45H59ClNPPd |
| Application | 2nd Generation Buchwald Precatalysts• Widely used for Suzuki-Miyaura cross-coupling reactions1,2,3,4 |
| Melting point | 202-210 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is XPhos Pd G2 used for?
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XPhos Pd G2 is primarily used as a second-generation Buchwald precatalyst for Suzuki-Miyaura cross-coupling reactions and other homogeneous palladium-catalysed transformations in chemical synthesis.
What is the CAS number and formula for XPhos Pd G2?
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The CAS number for XPhos Pd G2 is 1310584-14-5. The empirical formula (Hill notation) is C45H59ClNPPd.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies XPhos Pd G2 as a research-grade chemical. The exact purity is detailed in the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should XPhos Pd G2 be handled?
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XPhos Pd G2 is classified as a Warning substance. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including gloves and eye protection, and ensure adequate ventilation. Avoid breathing dust. In case of contact, rinse cautiously with water for several minutes.
Is XPhos Pd G2 a controlled substance?
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The provided data does not indicate that XPhos Pd G2 is a controlled substance.
How is XPhos Pd G2 packed, shipped, and exported?
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XPhos Pd G2 is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for XPhos Pd G2?
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To request a sample or a quotation for XPhos Pd G2, please contact our sales team through the website or by calling our office. Please provide your details and the quantity required.
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