Triprolidine hydrochloride
Triprolidine hydrochloride (CAS 6138-79-0, C19H22N2 · HCl) is a bioactive small molecule and H1 histaminergic inhibitor supplied by Tech Serve Solutions. With a molecular weight of 314.85, this compound is valuable in biochemical research, particularly in cell biology and neuroscience studies. It serves as a research tool for investigating histamine receptor interactions and their downstream effects in biological systems, offered at a high purity.
- IUPAC
- (E)-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride,trans-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride
- Synonyms
- (E)-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride, trans-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride

Histamine Receptor Research
Triprolidine hydrochloride is utilised as an H1 histaminergic inhibitor in research settings. It aids in understanding the role of histamine receptors in physiological processes such as long-term potentiation (LTP) in specific neuronal populations.
Neuroscience Studies
This compound is employed in neuroscience to investigate the intricate signaling pathways involving histamine and its receptors. Its application helps elucidate mechanisms within the central nervous system, including the tuberomammillary nucleus (TMN).
Biochemical Tool
As a bioactive small molecule, triprolidine hydrochloride serves as a versatile reagent in biochemical assays and cell biology experiments. It assists in probing cellular responses and molecular interactions.
| Molecular weight | 314.85 |
|---|---|
| Empirical formula | C19H22N2 · HCl |
| Assay | ≥99% |
| Solubility | alcohol: soluble1 in 1.5 of solventchloroform: soluble1 in less than 1 of solventH2O: soluble50 mg/mL, clear, colorless to yellow |
| Storage temperature | 2-8°C |
| Application | Triprolidine has been used as a H1 histaminergic inhibitor to study its effect on long-term potentiation (LTP) in tuberomammillary nucleus (TMN) neurons1. |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HRH1(3269) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triprolidine hydrochloride used for?
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Triprolidine hydrochloride is primarily used as a research tool, specifically as an H1 histaminergic inhibitor, to study its effects on biological processes like long-term potentiation (LTP) in neurons. It is employed in cell biology and neuroscience research.
What is the CAS number and chemical formula for Triprolidine hydrochloride?
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The CAS number for Triprolidine hydrochloride is 6138-79-0, and its chemical formula is C19H22N2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Triprolidine hydrochloride with an assay of ≥99%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling Triprolidine hydrochloride?
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Triprolidine hydrochloride is a Warning substance, classified with hazards H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, is essential. Ensure good ventilation and avoid breathing dust.
How is Triprolidine hydrochloride typically supplied and exported?
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Triprolidine hydrochloride is stored at 2-8°C. Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, capable of meeting international shipping requirements.
How can I request a sample or quote for Triprolidine hydrochloride?
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To request a sample or a quote for Triprolidine hydrochloride, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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