Triphenylphosphine oxide
Triphenylphosphine oxide (CAS 791-28-6), with the molecular formula (C6H5)3PO and a molar mass of 278.28 g/mol, is a stable, crystalline organophosphorus compound. It is widely recognised for its utility as a ligand in coordination chemistry and catalysis. Its polar nature and ability to coordinate with metal centres make it a valuable reagent in various synthetic transformations and inorganic applications.
- IUPAC
- Ph3PO,TPPO,Triphenyl phosphorus oxide,Triphenylphosphine monoxide
- Synonyms
- Ph3POTPPOTriphenyl phosphorus oxideTriphenylphosphine monoxide
Catalysis
Triphenylphosphine oxide serves as a ligand in organometallic catalysis, stabilising metal complexes and influencing reaction selectivity. It is employed in various catalytic cycles, including cross-coupling reactions and polymerisation.
Chemical Synthesis
This compound is a useful reagent in organic synthesis, particularly as a leaving group or activating agent in specific transformations. Its stable P=O bond makes it a convenient by-product in certain reactions.
Coordination Chemistry
It acts as a coordinating ligand for a wide range of metal ions, forming stable complexes. These complexes find applications in materials science and fundamental inorganic chemistry research.
| Molecular weight | 278.28 |
|---|---|
| Linear formula | (C6H5)3PO |
| Assay | ≥98.0% (HPLC) |
| Grade | purum |
| Solubility | methanol: soluble25 mg/mL, clear |
| Melting point | 150-157 °C(lit.)152-158 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 180 °C / 356 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triphenylphosphine oxide used for?
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Triphenylphosphine oxide is primarily used as a ligand in catalysis and coordination chemistry, and as a reagent in organic synthesis.
What is the CAS number and formula for Triphenylphosphine oxide?
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The CAS number is 791-28-6, and the linear formula is (C6H5)3PO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Triphenylphosphine oxide with a purity of ≥98.0% (HPLC) and a 'purum' grade. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Triphenylphosphine oxide be handled?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. This compound is classified with hazards including H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).
How is Triphenylphosphine oxide shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of handling international shipments of Triphenylphosphine oxide.
How can I request a sample or quote?
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Please contact our sales team directly to request a sample or a quotation for Triphenylphosphine oxide.
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