Trifluperidol hydrochloride
Trifluperidol hydrochloride (CAS: 2062-77-3) is a potent antipsychotic agent with the molecular formula C22H23F4NO2 · HCl and a molecular weight of 445.88 g/mol. Supplied as a white to off-white solid, this compound is primarily utilised as a research chemical for investigations into neurochemical pathways, particularly its interaction with dopamine and NMDA receptors. Its well-defined properties make it a valuable tool for neuroscience research.
- IUPAC
- 4′-Fluoro-4-[4-hydroxy-4-(α,α,α-trifluoro-m tolyl)piperidino]butyrophenone hydrochloride,R 2498,Triperidol

Neuroscience Research
Trifluperidol hydrochloride is used as a research tool to study the dopaminergic system and neurotransmission. Its antagonist properties at dopamine receptors are critical for understanding neurological processes and disorders.
NMDA Receptor Studies
Research has investigated the interaction of Trifluperidol hydrochloride with NMDA receptors in biological systems, such as rat brain membranes. This highlights its utility in exploring receptor pharmacology.
GPCR Modulator Research
As a GPCR modulator, this compound aids in the study of G protein-coupled receptor function, particularly relevant to dopamine signalling pathways in cell biology and neuroscience.
| Molecular weight | 445.88 |
|---|---|
| Empirical formula | C22H23F4NO2 · HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | DMSO: ≥20 mg/mLH2O: solubleethanol: moderately soluble |
| Application | The interaction of Trifluperidol hydrochloride with NMDA receptors was studied in rat brain buffy coat membranes.1 |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trifluperidol hydrochloride used for?
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Trifluperidol hydrochloride is primarily used in research settings for studies in neuroscience, cell signaling, and as a dopaminergic antagonist to investigate neurotransmission and receptor interactions.
What is the CAS number and chemical formula for Trifluperidol hydrochloride?
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The CAS number is 2062-77-3 and the chemical formula is C22H23F4NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trifluperidol hydrochloride with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the main safety considerations when handling Trifluperidol hydrochloride?
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Trifluperidol hydrochloride is classified with GHS07 symbol and a 'Warning' signal word, carrying the hazard statement H302 (Harmful if swallowed). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges, should be used. Refer to the Safety Data Sheet for full details.
How is Trifluperidol hydrochloride shipped and exported?
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Trifluperidol hydrochloride is classified as UN 2811, hazard class 6.1, with packing group II. Tech Serve Solutions handles the export of this chemical in compliance with international shipping regulations.
How can I request a sample or quote for Trifluperidol hydrochloride?
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Please contact our sales team to request a sample or obtain a quotation for Trifluperidol hydrochloride.
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