Trifluoromethanesulfonamide
Trifluoromethanesulfonamide (CAS: 421-85-2), with the chemical formula CF3SO2NH2 and a molecular weight of 149.09 g/mol, is a valuable organic building block. This compound is primarily utilised in chemical synthesis and research applications. Its structure makes it a key intermediate for introducing the trifluoromethanesulfonyl group into various molecules, enabling the development of new chemical entities with potentially useful properties.

Chemical Synthesis Intermediate
Trifluoromethanesulfonamide serves as a crucial building block in organic synthesis. It is employed to introduce the triflyl group (CF3SO2-) into target molecules, facilitating the construction of complex organic structures for various research and development purposes.
Reagent in Organic Chemistry
This compound functions as a reagent in diverse organic transformations. Its unique reactivity allows for specialised synthetic pathways, contributing to advancements in medicinal chemistry and materials science research.
Research and Development
Utilised in academic and industrial research laboratories, Trifluoromethanesulfonamide aids in exploring novel chemical reactions and synthesising potential drug candidates or functional materials.
| Molecular weight | 149.09 |
|---|---|
| Linear formula | CF3SO2NH2 |
| Assay | 95% |
| Melting point | 120-124 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CA2(760) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trifluoromethanesulfonamide used for?
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Trifluoromethanesulfonamide is primarily used as a building block and reagent in chemical synthesis and research and development applications, particularly for introducing the trifluoromethanesulfonyl group.
What is the CAS number and chemical formula for Trifluoromethanesulfonamide?
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The CAS number for Trifluoromethanesulfonamide is 421-85-2, and its chemical formula is CF3SO2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trifluoromethanesulfonamide with an assay of 95%. This product is intended for research and technical use and is not represented as USP, BP, EP, or pharmaceutical grade.
How should Trifluoromethanesulfonamide be handled safely?
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Handle Trifluoromethanesulfonamide with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. It is classified as harmful if swallowed and causes skin and eye irritation. Refer to the Safety Data Sheet for detailed handling information.
Does Tech Serve Solutions export Trifluoromethanesulfonamide?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Trifluoromethanesulfonamide, serving customers worldwide.
How can I request a sample or quote for Trifluoromethanesulfonamide?
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To request a sample or obtain a quote for Trifluoromethanesulfonamide, please contact our sales department through the website or by phone, providing your specific requirements.
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