Trifluoromethanesulfonyl chloride
Trifluoromethanesulfonyl chloride (CAS 421-83-0), molecular formula CF3SO2Cl, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- Triflyl chloride

| Molecular weight | 168.52 |
|---|---|
| Linear formula | CF3SO2Cl |
| Assay | ≥99% |
| Boiling point | 29-32 °C(lit.) |
| Density | 1.583 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.334(lit.) |
| Vapour pressure | 10.36 psi (20 °C) |
| Storage temperature | 2-8°C |
| Application | Ru(II) complex-catalyzed trifluoromethylating agent for aromatics1 and alkenes.2 |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trifluoromethanesulfonyl chloride?
+
Trifluoromethanesulfonyl chloride (CAS 421-83-0), molecular formula CF3SO2Cl, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.
What grades of Trifluoromethanesulfonyl chloride does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Trifluoromethanesulfonyl chloride in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of Trifluoromethanesulfonyl chloride?
+
Trifluoromethanesulfonyl chloride has CAS number 421-83-0 and molecular formula CF3SO2Cl. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for Trifluoromethanesulfonyl chloride?
+
Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
+
Yes. Every batch of Trifluoromethanesulfonyl chloride ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should Trifluoromethanesulfonyl chloride be stored?
+
Store Trifluoromethanesulfonyl chloride in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is Trifluoromethanesulfonyl chloride used for?
+
Trifluoromethanesulfonyl chloride is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for Trifluoromethanesulfonyl chloride?
+
Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis



