Trifluoromethane
Trifluoromethane (CAS 75-46-7), with the chemical formula CHF3, is a halogenated hydrocarbon. It is a gas at standard conditions, possessing a molecular weight of 70.01 g/mol. This compound finds utility as a specialty gas and a reagent in chemical synthesis, particularly within fluorination processes and the development of specialized materials. Its properties make it a valuable component in various industrial and research applications requiring precise chemical manipulation.
- IUPAC
- Fluoroform,HFC-23
- Synonyms
- FluoroformHFC-23

Chemical Synthesis Reagent
Trifluoromethane serves as a building block or reagent in organic synthesis, particularly for introducing the trifluoromethyl group or in the preparation of fluorinated compounds. Its controlled reactivity allows for specific transformations in the development of new molecules.
Specialty Gas Applications
As a specialty gas, Trifluoromethane is utilised in niche industrial processes and research environments where its unique physical and chemical properties are advantageous. This can include its use in plasma etching or as a component in specific gas mixtures for analytical purposes.
Refrigerant Research
Historically and in ongoing research, compounds with similar structures have been investigated for refrigerant properties. Trifluoromethane, also known as HFC-23, has been studied and used in specific low-temperature refrigeration applications, though its environmental impact is a consideration.
| Molecular weight | 70.01 |
|---|---|
| Linear formula | CHF3 |
| Assay | ≥98% |
| Boiling point | −84 °C(lit.) |
| Vapour pressure | 635 psi (21 °C) |
| Vapour density | 2.43 (vs air) |
| Melting point | −160 °C(lit.) |

Hazard statements
- H280Contains gas under pressure; may explode if heated
Precautionary statements
- P410Protect from sunlight
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Transport (UN / ADR) | UN 1984 2.2 |
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trifluoromethane (CHF3) used for?
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Trifluoromethane is primarily used as a specialty gas and a reagent in chemical synthesis, particularly for fluorination reactions and in the development of fluorinated materials. It has also been investigated for refrigerant applications.
What is the CAS number and chemical formula for Trifluoromethane?
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The CAS number for Trifluoromethane is 75-46-7, and its chemical formula is CHF3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trifluoromethane with an assay of ≥98%. We do not represent this product as USP, BP, or EP grade unless explicitly stated otherwise in the product documentation.
How should Trifluoromethane be handled safely?
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Trifluoromethane is supplied under pressure and may be a simple asphyxiant. It carries the GHS04 symbol and a Warning signal word. Hazard statement H280 indicates it contains gas under pressure; may explode if heated. Handling requires appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection as indicated by safety data sheets. Store in a well-ventilated place and keep cool, following P410 + P403 precautionary statements.
How is Trifluoromethane packed and shipped?
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Trifluoromethane is shipped as a compressed gas in cylinders, compliant with ADR regulations (UN 1984 2.2). TSS exports chemicals globally, adhering to all relevant shipping and customs regulations.
How can I request a sample or quote for Trifluoromethane?
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To request a sample or a quotation for Trifluoromethane, please contact our sales team through the website or by phone. Please provide your specific requirements and delivery details.
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