Triethylamine trihydrofluoride
Triethylamine trihydrofluoride (CAS 73602-61-6), with the linear formula (C2H5)3N · 3HF and a molecular weight of 161.21, is a premium reagent for fluorination reactions. It serves as a mild and selective source of fluoride, enabling the fluorination of a diverse range of organic compounds. This reagent is essential in various chemical synthesis pathways, particularly where precise control over fluorination is required.
- IUPAC
- Hydrogen fluoride triethylamine,TREAT-HF
- Synonyms
- Hydrogen fluoride triethylamineTREAT-HF

Fluorination of Organic Compounds
Triethylamine trihydrofluoride acts as a mild and selective fluorinating agent, suitable for a wide array of substrates. Its utility spans the synthesis of fluorinated intermediates and complex molecules.
Chemical Synthesis
As a versatile synthetic reagent, it is employed in organic chemistry laboratories for introducing fluorine atoms into molecules. Its controlled reactivity makes it valuable for specific synthetic transformations.
Specialty Fluorination Reactions
This compound is particularly useful for fluorination reactions where less aggressive reagents are required. A comprehensive review of its applications can be found in Aldrichimica Acta.
| Molecular weight | 161.21 |
|---|---|
| Linear formula | (C2H5)3N · 3HF |
| Assay | ~37% HF basis (T) |
| Boiling point | 70 °C/15 mmHg(lit.) |
| Density | 0.989 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.3915(lit.) |
| Application | Mild and selective reagent that has been used in the fluorination of a wide variety of compounds. For a review, see Aldrichimica Acta.1 |


Hazard statements
- H300Fatal if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2927 8(6.1) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28-35 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triethylamine trihydrofluoride primarily used for?
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Triethylamine trihydrofluoride is primarily used as a mild and selective reagent for the fluorination of a wide variety of organic compounds in chemical synthesis.
What is the CAS number and formula for Triethylamine trihydrofluoride?
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The CAS number is 73602-61-6 and the linear formula is (C2H5)3N · 3HF.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Triethylamine trihydrofluoride at a PREMIUM quality level, with an assay of approximately 37% HF basis (titration). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should Triethylamine trihydrofluoride be handled safely?
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Handling requires extreme caution due to severe toxicity and corrosivity. Users must wear full protective equipment including a faceshield, full-face respirator, chemical-resistant gloves, and goggles. Refer to the safety data sheet for detailed information on hazards and protective measures.
Is Triethylamine trihydrofluoride a controlled substance?
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The provided data does not indicate that Triethylamine trihydrofluoride is a controlled substance. However, users should always comply with local regulations.
How is Triethylamine trihydrofluoride typically packed and exported?
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Tech Serve Solutions exports fine chemicals globally, adhering to international shipping regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a quote or a sample?
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To request a quote or a sample of Triethylamine trihydrofluoride, please contact our sales team through the website or by phone.
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