Triethyl(trifluoromethyl)silane
Triethyl(trifluoromethyl)silane (CAS: 120120-26-5) is a trifluoromethylating reagent with the linear formula (C2H5)3SiCF3 and a molecular weight of 184.27 g/mol. This compound is primarily utilised in organic synthesis for the introduction of the trifluoromethyl group onto aryl iodides and in trialkylsilylation reactions. It also finds application in the deposition of perfluoro-methyl silica films. Tech Serve Solutions supplies this reagent at a 98% purity assay.
- IUPAC
- (Trifluoromethyl)triethylsilane,Triethylsilyl trifluoromethane
- Synonyms
- (Trifluoromethyl)triethylsilaneTriethylsilyl trifluoromethane

Trifluoromethylation of Aryl Iodides
This silane serves as a reactant for the efficient introduction of the trifluoromethyl group (CF3) onto aryl iodide substrates, a key transformation in medicinal chemistry and materials science.
Trialkylsilylation Reactions
Triethyl(trifluoromethyl)silane is employed in various silylation reactions, enabling the introduction of the triethylsilyl moiety into organic molecules.
Perfluoro-methyl Silica Film Deposition
The compound is utilised in processes for the deposition of specialised perfluoro-methyl silica films, which possess unique surface properties for advanced applications.
| Molecular weight | 184.27 |
|---|---|
| Linear formula | (C2H5)3SiCF3 |
| Assay | 98% |
| Boiling point | 56-57 °C/60 mmHg(lit.) |
| Density | 0.98 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.382(lit.) |
| Application | Reactant for:• Trifluoromethylation of aryl iodides1• Trialkylsilylation reactions2• Used for deposition of perfluoro-methyl silica films3 |

Hazard statements
- H225Highly flammable liquid and vapour
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 0 °C / 32 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F |
| Risk statements (R) | 11 |
| Safety statements (S) | 16-23-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triethyl(trifluoromethyl)silane used for?
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Triethyl(trifluoromethyl)silane is used as a reactant for the trifluoromethylation of aryl iodides and in trialkylsilylation reactions. It is also used for the deposition of perfluoro-methyl silica films.
What is the CAS number and formula for Triethyl(trifluoromethyl)silane?
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The CAS number for Triethyl(trifluoromethyl)silane is 120120-26-5 and its linear formula is (C2H5)3SiCF3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Triethyl(trifluoromethyl)silane at a 98% purity assay. We do not represent this product as meeting any pharmacopoeia standards such as USP, BP, or EP.
How should Triethyl(trifluoromethyl)silane be handled safely?
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Triethyl(trifluoromethyl)silane is a highly flammable liquid and vapour (H225). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area, away from ignition sources.
Is Triethyl(trifluoromethyl)silane flammable?
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Yes, Triethyl(trifluoromethyl)silane is highly flammable with a flash point of 0 °C (32 °F) and is classified under hazard statement H225.
How is Triethyl(trifluoromethyl)silane packed and shipped?
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Triethyl(trifluoromethyl)silane is packed and shipped as a flammable liquid, UN 1993, Packing Group II. Please consult our shipping department for specific export regulations and capabilities.
How can I request a quote or sample for Triethyl(trifluoromethyl)silane?
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To request a quote or sample for Triethyl(trifluoromethyl)silane, please contact our sales team through the website or by phone, referencing the product name and CAS number 120120-26-5.
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