Triethylene glycol di(p-toluenesulfonate)
Triethylene glycol di(p-toluenesulfonate) (CAS 19249-03-7) is an organic compound with a molecular weight of 458.55. It functions as a tosylate ester, serving as a valuable building block in organic synthesis. Its structure, featuring two tosylate groups attached to a triethylene glycol backbone, makes it useful for introducing specific functionalities in chemical reactions. This compound is primarily utilised in chemical research and development.
- IUPAC
- 2,2′-(Ethylenedioxy)diethyl ditosylate,Triethylene glycol ditosylate
- Synonyms
- 2,2′-(Ethylenedioxy)diethyl ditosylateTriethylene glycol ditosylate

Organic Synthesis Reagent
Utilised as a difunctional electrophile in organic synthesis. The tosylate groups are excellent leaving groups, facilitating nucleophilic substitution reactions for the formation of new carbon-heteroatom or carbon-carbon bonds.
Cross-linking Agent
Can serve as a cross-linking agent in polymer chemistry or material science, where its difunctional nature allows it to bridge polymer chains or functionalise surfaces.
Intermediate in Pharmaceutical Research
May be employed as an intermediate in the synthesis of complex organic molecules, including potential pharmaceutical candidates, owing to its reactive tosylate moieties.
| Molecular weight | 458.55 |
|---|---|
| Linear formula | (CH3C6H4SO3CH2CH2OCH2-)2 |
| Assay | ≥98.0% (HPLC) |
| Melting point | 78-82 °C(lit.)78-82 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triethylene glycol di(p-toluenesulfonate) used for?
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Triethylene glycol di(p-toluenesulfonate) is primarily used as a building block in organic synthesis and as a cross-linking agent. Its tosylate groups act as excellent leaving groups in nucleophilic substitution reactions.
What is the CAS number and formula for Triethylene glycol di(p-toluenesulfonate)?
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The CAS number is 19249-03-7. The linear formula is (CH3C6H4SO3CH2CH2OCH2-)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Triethylene glycol di(p-toluenesulfonate) with a purity of ≥98.0% by HPLC. This is a technical/research grade material and is not represented as USP, BP, or EP.
How should Triethylene glycol di(p-toluenesulfonate) be handled?
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Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is classified with hazard statements H315, H319, and H335.
Is Triethylene glycol di(p-toluenesulfonate) a controlled substance?
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The provided data does not indicate that Triethylene glycol di(p-toluenesulfonate) is a controlled substance.
How is Triethylene glycol di(p-toluenesulfonate) packed and shipped?
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This chemical is packed and exported according to standard international regulations for hazardous chemicals. Specific packaging details can be provided upon request.
How can I request a sample or quote for Triethylene glycol di(p-toluenesulfonate)?
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Please contact our sales team through the website or by phone to request a sample or a formal quotation for Triethylene glycol di(p-toluenesulfonate).
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