Triethylene glycol dimethyl ether
Triethylene glycol dimethyl ether (CAS: 112-49-2), with the molecular formula CH3O(CH2CH2O)3CH3 and a molecular weight of 178.23 g/mol, is a versatile organic solvent. Known for its high boiling point and stability, it serves as an excellent reaction medium and solvent in various chemical syntheses. This ether is a valuable building block for organic chemistry applications.
- IUPAC
- 1,2-Bis(2-methoxyethoxy)ethane,Dimethyltriglycol,Triglyme
- Synonyms
- 1,2-Bis(2-methoxyethoxy)ethaneDimethyltriglycolTriglyme

Organic Synthesis
Triethylene glycol dimethyl ether functions as a high-boiling solvent and reaction medium, facilitating various organic transformations. Its ability to solvate cations makes it useful in reactions involving organometallic reagents.
Chemical Research
This compound is employed as a reagent and solvent in laboratory settings for research and development purposes. Its properties are beneficial for studies in coordination chemistry and reaction mechanism investigations.
Building Block
As an organic building block, it can be incorporated into more complex molecular structures. Its ether linkages provide specific chemical reactivity and physical properties for synthetic targets.
| Molecular weight | 178.23 |
|---|---|
| Linear formula | CH3O(CH2CH2O)3CH3 |
| Assay | 98% |
| Grade | Vetec™ reagent grade |
| Boiling point | 216 °C(lit.) |
| Density | 0.986 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.423(lit.) |
| Melting point | −45 °C(lit.) |
| Vapour density | >4.7 (vs air) |
| Autoignition temp | 375 °F |

Hazard statements
- H360DF
Precautionary statements
- P201Obtain special instructions before use
- P308IF exposed or concerned
| Flash point | 111 °C / 231.8 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 61-19-62 |
| Safety statements (S) | 53-45 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triethylene glycol dimethyl ether used for?
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Triethylene glycol dimethyl ether is used as a high-boiling solvent, reaction medium in organic synthesis, and as an organic building block in chemical research and development.
What is the CAS number and chemical formula for Triethylene glycol dimethyl ether?
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The CAS number is 112-49-2, and the chemical formula is CH3O(CH2CH2O)3CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Triethylene glycol dimethyl ether in Vetec™ reagent grade with an assay of 98%. It is not represented as USP, BP, or EP grade.
What are the key safety considerations for Triethylene glycol dimethyl ether?
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Triethylene glycol dimethyl ether is classified as a Danger hazard, indicated by GHS08. It carries the hazard statement H360Df, meaning it may damage fertility or the unborn child and is suspected of doing so. It may also form explosive peroxides. Handle with appropriate personal protective equipment and ventilation. Refer to the Safety Data Sheet for detailed handling instructions.
How are chemicals from Tech Serve Solutions packed and exported?
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Tech Serve Solutions packs and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all relevant shipping and safety regulations.
How can I request a quote or sample for Triethylene glycol dimethyl ether?
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To request a quote or sample, please use the contact form on our website or reach out to our sales team directly with your requirements.
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