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Triethyl 4-phosphonocrotonate, mixture of isomers

CAS 10236-14-3(C2H5O)2P(O)CH2CH=CHCO2C2H5Chemical Synthesis

Triethyl 4-phosphonocrotonate, mixture of isomers (CAS 10236-14-3), molecular formula (C2H5O)2P(O)CH2CH=CHCO2C2H5, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.

IUPAC
4-(Diethoxyphosphinyl)-2-butenoic acid ethyl ester,4-Phosphonocrotonic acid triethyl ester
Triethyl 4-phosphonocrotonate, mixture of isomers
C-C Bond FormationChemical SynthesisOlefinationSynthetic Reagents
01 /Properties
Molecular weight250.23
Linear formula(C2H5O)2P(O)CH2CH=CHCO2C2H5
Assay90%
Boiling point135 °C/0.4 mmHg(lit.)
Density1.128 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.455(lit.)
ApplicationReactant for: • Iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptase1• Stereoselective preparation of C1-C19 fragment of macrolide antibiotic aplyronine A using diastereoselective Nozaki-Hiyama-Kishi coupling reactions2• Orally bioavailable GPR40 agonist synthesis3• Synthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A24• Preaparation of mGlu4R agonists5• Dearomatizing cyclization of nicotinyl-substituted esters and ketones6
02 /Safety & handling
Harmful / irritant
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point113 °C / 235.4 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

03 /Identifiers & registry
CAS number
10236-14-3
MDL number
MFCD00009192
PubChem substance
24847263
04 /Quality & supply

Documentation

Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Triethyl 4-phosphonocrotonate, mixture of isomers?

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Triethyl 4-phosphonocrotonate, mixture of isomers (CAS 10236-14-3), molecular formula (C2H5O)2P(O)CH2CH=CHCO2C2H5, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.

What grades of Triethyl 4-phosphonocrotonate, mixture of isomers does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Triethyl 4-phosphonocrotonate, mixture of isomers in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.

What is the CAS number and molecular formula of Triethyl 4-phosphonocrotonate, mixture of isomers?

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Triethyl 4-phosphonocrotonate, mixture of isomers has CAS number 10236-14-3 and molecular formula (C2H5O)2P(O)CH2CH=CHCO2C2H5. Full specifications appear in the table above and in the Certificate of Analysis.

What is the typical minimum order quantity and lead time for Triethyl 4-phosphonocrotonate, mixture of isomers?

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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.

Do you provide a Certificate of Analysis (CoA) with each shipment?

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Yes. Every batch of Triethyl 4-phosphonocrotonate, mixture of isomers ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.

How should Triethyl 4-phosphonocrotonate, mixture of isomers be stored?

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Store Triethyl 4-phosphonocrotonate, mixture of isomers in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.

What is Triethyl 4-phosphonocrotonate, mixture of isomers used for?

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Triethyl 4-phosphonocrotonate, mixture of isomers is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.

How do I request a quote for Triethyl 4-phosphonocrotonate, mixture of isomers?

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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.

Need Triethyl 4-phosphonocrotonate, mixture of isomers in a specific grade or volume?

Request a quote