Tri-tert-butylphosphine
Tri-tert-butylphosphine (CAS 13716-12-6), molecular formula [(CH3)3C]3P, is a high-purity chemical supplied by Tech Serve Solutions for catalysis & inorganic applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- P(t-Bu)3

| Molecular weight | 202.32 |
|---|---|
| Linear formula | [(CH3)3C]3P |
| Assay | 98% |
| Boiling point | 102-103 °C/13 mmHg(lit.) |
| Density | 0.834 g/mL at 20 °C(lit.) |
| Concentration | 1.0 M in toluene |
| Application | Preferred ligand in the palladium-catalyzed coupling of arylboronic acids with phenyliodonium ylides of hydroxyquinones.1 Also used with Pd2(dba)3 for the α-arylation of trimethylsilyl enol ethers with aryl halides.2 |
| Melting point | 30-35 °C(lit.) |


Hazard statements
- H250Catches fire spontaneously if exposed to air
- H314Causes severe skin burns and eye damage
Precautionary statements
- P222Do not allow contact with air
- P231Handle under inert gas
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
- P422
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 2846 4.2 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 17-34 |
| Safety statements (S) | 16-26-27-36/37/39-43-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Ligand For | Addition ReactionsBuchwald-Hartwig Cross Coupling ReactionHeck ReactionNegishi CouplingSonogashira CouplingStille CouplingSuzuki-Miyaura Coupling |
|---|
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tri-tert-butylphosphine?
+
Tri-tert-butylphosphine (CAS 13716-12-6), molecular formula [(CH3)3C]3P, is a high-purity chemical supplied by Tech Serve Solutions for catalysis & inorganic applications, to USP, BP and EP standards.
What grades of Tri-tert-butylphosphine does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tri-tert-butylphosphine in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of Tri-tert-butylphosphine?
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Tri-tert-butylphosphine has CAS number 13716-12-6 and molecular formula [(CH3)3C]3P. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for Tri-tert-butylphosphine?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of Tri-tert-butylphosphine ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should Tri-tert-butylphosphine be stored?
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Store Tri-tert-butylphosphine in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is Tri-tert-butylphosphine used for?
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Tri-tert-butylphosphine is used in catalysis & inorganic applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for Tri-tert-butylphosphine?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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