trans-N-(2-Pyridylmethylene)aniline
trans-N-(2-Pyridylmethylene)aniline (CAS: 40468-86-8; Formula: C12H10N2; MW: 182.22) is a versatile organic compound, primarily employed as a building block in chemical synthesis. Its structure, featuring a pyridine ring and an aniline moiety linked by an imine group, makes it valuable for constructing more complex heterocyclic molecules. This compound is suitable for research and development applications where precise molecular architectures are required.
- IUPAC
- (E)-N-((Pyridin-2-yl)methylene)benzenamine
- Synonyms
- (E)-N-((Pyridin-2-yl)methylene)benzenamine

Heterocyclic Synthesis
As a pyridine derivative and an imine, trans-N-(2-Pyridylmethylene)aniline serves as a key intermediate in the synthesis of novel heterocyclic compounds. It can participate in various cyclisation and functionalisation reactions to build complex ring systems.
Organic Synthesis Reagent
This compound acts as a valuable building block in general organic synthesis. Its reactive imine functionality and aromatic rings allow for diverse transformations, contributing to the development of new chemical entities.
Ligand Development
The presence of nitrogen atoms in both the pyridine and imine groups suggests potential applications in coordination chemistry, where it may function as a ligand for metal complex formation.
| Molecular weight | 182.22 |
|---|---|
| Empirical formula | C12H10N2 |
| Assay | 97% |
| Boiling point | 97-101/0.1 mmHg |
| Melting point | 35-40 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is trans-N-(2-Pyridylmethylene)aniline used for?
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trans-N-(2-Pyridylmethylene)aniline is primarily used as a building block in organic and heterocyclic synthesis for research and development purposes.
What are the CAS number and formula for trans-N-(2-Pyridylmethylene)aniline?
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The CAS number is 40468-86-8 and the molecular formula is C12H10N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies trans-N-(2-Pyridylmethylene)aniline with an assay of 97%. This is a technical grade suitable for research and chemical synthesis. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling this compound?
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This compound is classified with GHS07 and carries a Warning signal word. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, faceshields, and gloves, should be used. Ensure adequate ventilation.
How is trans-N-(2-Pyridylmethylene)aniline shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, offering reliable shipping and export services for trans-N-(2-Pyridylmethylene)aniline.
How can I request a sample or quote for this chemical?
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To request a sample or a quotation for trans-N-(2-Pyridylmethylene)aniline, please contact our sales department through the website or by phone.
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