trans-N,N,N′,N′-Tetramethyl-2-butene-1,4-diamine
Trans-N,N,N′,N′-Tetramethyl-2-butene-1,4-diamine (CAS: 111-52-4) is an organic diamine with the linear formula (CH3)2NCH2CH=CHCH2N(CH3)2 and a molecular weight of 142.24 g/mol. This compound serves as a valuable building block in organic synthesis. Its chemical structure, featuring two tertiary amine groups and an internal double bond, makes it suitable for various chemical transformations and the creation of more complex molecules.
- Synonyms
- N′-Tetramethyl-2-butene-1,4-diamine111-52-4(CH3)2NCH2CH=CHCH2N(CH3)2

Organic Synthesis Intermediate
This diamine functions as a key intermediate in the synthesis of diverse organic compounds. Its reactive amine functionalities allow for alkylation, acylation, and other nucleophilic substitution reactions.
Building Block for Nitrogen-Containing Compounds
The presence of two tertiary amine groups makes it an excellent precursor for constructing complex nitrogen-containing molecules, including heterocycles and polymers.
Research and Development
Utilised in research laboratories for exploring novel chemical reactions and developing new materials. Its specific structure lends itself to applications in medicinal chemistry and materials science.
| Molecular weight | 142.24 |
|---|---|
| Linear formula | (CH3)2NCH2CH=CHCH2N(CH3)2 |
| Assay | 98% |
| Boiling point | 172-173 °C/723 mmHg(lit.) |
| Density | 0.82 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.441(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 54 °C / 129.2 °F |
| Transport (UN / ADR) | UN 2734 8/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trans-N,N,N′,N′-Tetramethyl-2-butene-1,4-diamine used for?
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Trans-N,N,N′,N′-Tetramethyl-2-butene-1,4-diamine is primarily used as a building block and intermediate in organic synthesis for creating complex nitrogen-containing molecules and in research and development applications.
What is the CAS number and formula for Trans-N,N,N′,N′-Tetramethyl-2-butene-1,4-diamine?
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The CAS number is 111-52-4, and the linear formula is (CH3)2NCH2CH=CHCH2N(CH3)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trans-N,N,N′,N′-Tetramethyl-2-butene-1,4-diamine with an assay of 98%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Trans-N,N,N′,N′-Tetramethyl-2-butene-1,4-diamine be handled safely?
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This compound is classified as corrosive and flammable. It can cause severe skin burns and eye damage. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for full details.
How is Trans-N,N,N′,N′-Tetramethyl-2-butene-1,4-diamine packed and shipped?
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Trans-N,N,N′,N′-Tetramethyl-2-butene-1,4-diamine is packed and shipped according to UN 2734, Class 8/PG 2 regulations, ensuring safe transit and compliance with international export standards.
How can I request a sample or quote for Trans-N,N,N′,N′-Tetramethyl-2-butene-1,4-diamine?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team via our website or direct contact details, specifying the product name and CAS number (111-52-4).
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