trans-2-(4-Chlorophenyl)vinylboronic acid pinacol ester
trans-2-(4-Chlorophenyl)vinylboronic acid pinacol ester (CAS: 223919-54-8) is an organoboron compound with the molecular formula C14H18BClO2 and a molecular weight of 264.56. This chemical is a valuable building block in organic synthesis, particularly within the pharmaceutical and agrochemical industries. It serves as a key intermediate for introducing the 4-chlorostyryl moiety into complex molecules via cross-coupling reactions.
- IUPAC
- 2-[2-(4-Chlorophenyl)vinyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane,2-[(1E)-2-(4-Chlorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- Synonyms
- 2-[2-(4-Chlorophenyl)vinyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane2-[(1E)-2-(4-Chlorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Suzuki-Miyaura Cross-Coupling Reactions
This boronate ester is a versatile coupling partner in palladium-catalysed Suzuki-Miyaura reactions. It enables the formation of new carbon-carbon bonds, crucial for constructing complex organic frameworks used in drug discovery and materials science.
Pharmaceutical Intermediate Synthesis
Its structure makes it a useful intermediate in the synthesis of active pharmaceutical ingredients (APIs). The 4-chlorophenylvinyl group can be incorporated into potential drug candidates targeting various therapeutic areas.
Agrochemical Development
This compound can serve as a building block for novel agrochemicals, contributing to the development of new pesticides, herbicides, or fungicides.
Organic Synthesis Reagent
As an organometallic reagent, it facilitates a range of synthetic transformations, offering chemists a reliable method for functionalizing molecules with a specific substituted styrene unit.
| Molecular weight | 264.56 |
|---|---|
| Empirical formula | C14H18BClO2 |
| Assay | 97% |
| Melting point | 88-92 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is trans-2-(4-Chlorophenyl)vinylboronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and serves as an intermediate in the development of pharmaceuticals and agrochemicals.
What is the CAS number and molecular formula?
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The CAS number is 223919-54-8, and the molecular formula is C14H18BClO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. This is a technical/research grade chemical and is not represented as USP, BP, or EP.
What are the safety and handling considerations?
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According to GHS classifications, this substance is a WGK 1 (Water Hazard Class 1) in Germany, indicating it is hazardous to aquatic life. Standard laboratory safety precautions, including appropriate personal protective equipment and ventilation, should be employed when handling.
How is this chemical packed and exported?
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Tech Serve Solutions packs and exports chemicals according to international shipping regulations to ensure safe and compliant transit.
How can I request a sample or quote?
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Please contact our sales team via the website or by phone to request a sample or a formal quotation for trans-2-(4-Chlorophenyl)vinylboronic acid pinacol ester.
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