Aldosterone

CAS 52-39-1C21H28O5Chemical Synthesis

Aldosterone (CAS: 52-39-1; Formula: C21H28O5) is a mineralocorticoid steroid hormone synthesized in the adrenal cortex. It plays a critical role in regulating blood pressure, electrolyte balance, and fluid homeostasis. As the d-isomer, this compound is biologically active. Aldosterone is essential for maintaining sodium and potassium levels, influencing water reabsorption in the kidneys. It is utilized in biochemical research for studying endocrine functions and related physiological processes.

IUPAC: 11β,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al,11β,21-Dihydroxypregn-4-ene-3,18,20-trione,18-Aldocorticosterone,Reichstein X
Synonyms: 11β,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al11β,21-Dihydroxypregn-4-ene-3,18,20-trione18-AldocorticosteroneReichstein X

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Aldosterone (C21H28O5) — chemical structure, CAS 52-39-1; Chemistry, fine chemical supplied by Tech Serve Solutions

A-AMAldehydesBioactive Small MoleculesBuilding BlocksC13-C60Carbonyl CompoundsCell BiologyChemical SynthesisCorticosteroidCytokines

01 /Applications

Endocrine Research

Used as a reference standard or research tool in studies investigating the endocrine system, particularly focusing on the adrenal cortex and mineralocorticoid receptor pathways. Its biological activity makes it valuable for in vitro and in vivo endocrine research.

Biochemical Studies

Applicable in biochemical assays and experiments aimed at understanding hormone action, signal transduction, and the molecular mechanisms of electrolyte and fluid balance regulation. It serves as a key molecule in metabolic and physiological research.

Physiological Investigations

Employed in research to explore the physiological effects of aldosterone on renal function, cardiovascular health, and the interplay between hormones and the body's fluid balance. Essential for studying conditions related to mineralocorticoid imbalances.

02 /Properties

Molecular weight	360.44
Empirical formula	C21H28O5
Assay	≥95% (HPLC)
Application	The d-isomer of aldosterone is considered to be the biologically active isomer.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

52-39-1

MDL number

MFCD00051136

PubChem substance

24891458

Beilstein registry

3224996

05 /Additional specifications

Gene Information	human ... SERPINA6(866)rat ... Ar(24208), Nr3c2(25672)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Aldosterone used for?

Aldosterone is used in biochemical and physiological research to study endocrine functions, electrolyte balance, fluid homeostasis, and its role in regulating blood pressure. The d-isomer is the biologically active form.

What is the CAS number and formula for Aldosterone?

The CAS number for Aldosterone is 52-39-1, and its empirical formula is C21H28O5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Aldosterone with a minimum purity of ≥95% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.

How should Aldosterone be handled safely?

Handle Aldosterone with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany 3.

Is Aldosterone a controlled substance?

The provided data does not indicate that Aldosterone is a controlled substance. Please consult relevant regulatory guidelines for specific applications.

How is Aldosterone packed and shipped?

Aldosterone is exported by TSS in accordance with international shipping regulations for chemical compounds. Specific packing details can be provided upon request.

How can I request a quote or sample for Aldosterone?

To request a quote or sample for Aldosterone, please contact the TSS sales team through our website or by phone. Our export specialists will assist you.