Potassium phenyltrifluoroborate
Potassium phenyltrifluoroborate (CAS 153766-81-5; C6H5BF3K) is an organoboron compound with a molecular weight of 184.01 g/mol. It is a stable and versatile aryl trifluoroborate salt, frequently employed as a reagent in organic synthesis. Its primary applications lie in cross-coupling reactions, facilitating the formation of carbon-carbon and carbon-heteroatom bonds. This compound is a valuable building block for creating complex organic molecules.
Suzuki-Miyaura Cross-Coupling Reactions
Potassium phenyltrifluoroborate serves as an effective arylating agent in palladium-catalyzed Suzuki-Miyaura coupling reactions. It enables the efficient synthesis of biaryls and related structures by coupling with aryl or vinyl halides and pseudohalides.
Conjugate Addition Reactions
This trifluoroborate salt can participate in conjugate addition reactions, allowing for the introduction of the phenyl group to Michael acceptors. This is a key transformation in the construction of substituted carbocyclic and heterocyclic frameworks.
Synthesis of Pharmaceutical Intermediates
The compound is utilized in the multi-step synthesis of complex organic molecules, including advanced intermediates for active pharmaceutical ingredients (APIs). Its reactivity profile supports the development of novel drug candidates.
Material Science Research
Potassium phenyltrifluoroborate can be employed in the synthesis of novel organic materials, such as those used in organic electronics or polymers, where precise structural control is required.
| Molecular weight | 184.01 |
|---|---|
| Empirical formula | C6H5BF3K |
| Assay | 95% |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Potassium phenyltrifluoroborate used for?
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Potassium phenyltrifluoroborate is primarily used as a reagent in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions like the Suzuki-Miyaura coupling, and in conjugate addition reactions for constructing complex organic molecules and pharmaceutical intermediates.
What is the CAS number and chemical formula for Potassium phenyltrifluoroborate?
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The CAS number is 153766-81-5 and the chemical formula is C6H5BF3K.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Potassium phenyltrifluoroborate with an assay of 95%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Potassium phenyltrifluoroborate be handled?
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Potassium phenyltrifluoroborate is classified as irritating to the skin, eyes, and respiratory system (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), safety eyeshields, and gloves. Ensure adequate ventilation, avoid breathing dust, and prevent contact with skin and eyes. Wash thoroughly after handling.
How is Potassium phenyltrifluoroborate packed and shipped?
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Potassium phenyltrifluoroborate is carefully packed to ensure safe transit. As a supplier and exporter, Tech Serve Solutions adheres to all relevant shipping regulations for chemical products.
How can I request a quote or sample for Potassium phenyltrifluoroborate?
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To request a quote or a sample of Potassium phenyltrifluoroborate, please contact our sales department through the website or by phone, providing your contact details and the quantity required.
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