Toloxatone
Toloxatone (CAS: 29218-27-7, C11H13NO3) is a selective, reversible inhibitor of monoamine oxidase A (MAO-A). This bioactive small molecule is crucial in neuroscience research for studying neurotransmitter metabolism and monoamine oxidase pathways. With a molecular weight of 207.23 g/mol, Toloxatone serves as a valuable research tool in areas such as cell signaling, drug metabolism, and the development of therapeutics targeting neurological disorders.
- IUPAC
- 5-(Hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone,Humoryl
Neuroscience Research Tool
Toloxatone is utilized in neuroscience to investigate the roles of monoamine oxidase A in neurotransmitter regulation. Its selective inhibition allows researchers to probe the effects of MAO-A activity on cellular signaling and neuronal function.
Enzyme Inhibition Studies
As a selective MAO-A inhibitor, Toloxatone is employed in biochemical and pharmacological studies to understand enzyme kinetics and substrate interactions. This aids in the development of new enzyme-targeted therapies.
Drug Metabolism Research
The compound is relevant in studies concerning drug and xenobiotic metabolism. Researchers use Toloxatone to explore pathways involving oxidative enzymes and their impact on the efficacy and pharmacokinetics of other substances.
| Molecular weight | 207.23 |
|---|---|
| Empirical formula | C11H13NO3 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Toloxatone used for?
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Toloxatone is primarily used as a research chemical, specifically as a selective and reversible inhibitor of monoamine oxidase A (MAO-A). It is valuable in neuroscience research for studying neurotransmitter metabolism, cell signaling, and enzyme inhibition.
What is the CAS number and chemical formula for Toloxatone?
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The CAS number for Toloxatone is 29218-27-7, and its chemical formula is C11H13NO3.
What grade and purity does Tech Serve Solutions supply for Toloxatone?
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Tech Serve Solutions supplies Toloxatone with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should Toloxatone be handled safely?
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Toloxatone is classified as harmful if swallowed (H302). When handling, it is recommended to wear a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
How is Toloxatone shipped and exported?
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Toloxatone is typically stored at 2-8°C in a desiccated state. Tech Serve Solutions can export this chemical globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Toloxatone?
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To request a sample or a quote for Toloxatone, please contact our sales team through the website or by phone. We are happy to assist with your research needs.
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