Tetraphenylbiphosphine
Tetraphenylbiphosphine (CAS 1101-41-3) is a phosphine compound with the molecular formula (C₆H₅)₂PP(C₆H₅)₂ and a molar mass of 370.36 g/mol. This white solid is primarily utilised as a catalyst and initiator in various chemical synthesis applications, including selective amino acid formation, hydrogenation reactions, and catalytic polymerisation. It also serves as a cocatalyst in rhodium-catalyzed hydroformylation processes.
- IUPAC
- Tetraphenyldiphosphane
- Synonyms
- Tetraphenyldiphosphane

Catalyst for Selective Unsaturated Amino Acid Formation
Tetraphenylbiphosphine acts as a catalyst to facilitate the selective formation of unsaturated amino acids, a crucial process in organic synthesis.
Hydrogenation Reactions
This compound serves as a catalyst in various hydrogenation reactions, contributing to the reduction of unsaturated compounds.
Initiator in Catalytic Polymerization
It functions as an initiator in catalytic polymerization reactions, playing a role in the synthesis of polymers.
Cocatalyst in Hydroformylation
Tetraphenylbiphosphine is employed as a cocatalyst in rhodium-catalyzed hydroformylation, an important industrial process for producing aldehydes.
| Molecular weight | 370.36 |
|---|---|
| Linear formula | (C6H5)2PP(C6H5)2 |
| Boiling point | 258-260 °C/1 mmHg(lit.) |
| Application | Catalyst for:• Selective formation of unsaturated amino acids1• Hydrogenation reactions2Initiator in catalytic polymerization reactions3Cocatalyst for rhodium-catalyzed hydroformylation4 |
| Melting point | 120-122 °C (sealed tube)(lit.) |

Hazard statements
- H250Catches fire spontaneously if exposed to air
Precautionary statements
- P222Do not allow contact with air
- P231Handle under inert gas
- P422
| Protective equipment | Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2846 4.2 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F |
| Risk statements (R) | 17 |
| Safety statements (S) | 6-16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetraphenylbiphosphine used for?
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Tetraphenylbiphosphine (CAS 1101-41-3) is used as a catalyst and initiator in various chemical synthesis applications, including selective formation of unsaturated amino acids, hydrogenation reactions, catalytic polymerization, and as a cocatalyst in rhodium-catalyzed hydroformylation.
What is the CAS number and chemical formula for Tetraphenylbiphosphine?
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The CAS number for Tetraphenylbiphosphine is 1101-41-3, and its linear formula is (C₆H₅)₂PP(C₆H₅)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetraphenylbiphosphine. The assay and grade are not specified in the provided data, and therefore TSS does not represent this product as USP, BP, EP, or for any specific pharmacopoeia or food applications. It is typically supplied as a research or technical grade material.
How should Tetraphenylbiphosphine be handled?
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Tetraphenylbiphosphine is classified as pyrophoric (H250), meaning it may ignite spontaneously in air. It requires careful handling under an inert atmosphere. Recommended personal protective equipment includes eyeshields, faceshields, and gloves. Ensure proper ventilation and avoid contact with ignition sources.
How is Tetraphenylbiphosphine packed and shipped?
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Tetraphenylbiphosphine is shipped as UN 2846, Hazard Class 4.2, Packing Group I, indicating it is a substance liable to spontaneous combustion. It is packed and exported by Tech Serve Solutions in compliance with relevant dangerous goods regulations.
How can I request a quote or sample for Tetraphenylbiphosphine?
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To request a quote or a sample of Tetraphenylbiphosphine, please contact our sales team through the website or by phone. Provide your inquiry details, including the product name and CAS number.
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