(tert-Butyldimethylsilyloxy)acetaldehyde
(tert-Butyldimethylsilyloxy)acetaldehyde (CAS: 102191-92-4) is an organic compound with the linear formula (CH 3 )3CSi(CH 3 )2OCH 2 CHO and a molecular weight of 174.31 g/mol. This aldehyde, featuring a silyl ether protecting group, serves as a valuable building block in organic synthesis. It is particularly employed in the construction of complex molecular architectures, contributing to the development of novel compounds for research and development.
Organic Synthesis Intermediate
This silylated acetaldehyde derivative is instrumental in multi-step organic syntheses. Its protected aldehyde functionality allows for selective reactions, making it a versatile tool for chemists constructing complex molecules.
Natural Product Synthesis
It has been utilised in the construction of key structural subunits for complex natural products. For instance, it was employed in the synthesis of the tetrahydropyran core of the marine natural product (–)-dactylodide.
Building Block for Heterocycles
The compound's structure makes it suitable for incorporation into various heterocyclic ring systems, which are prevalent in pharmaceuticals and agrochemicals.
| Molecular weight | 174.31 |
|---|---|
| Linear formula | (CH3)3CSi(CH3)2OCH2CHO |
| Assay | 90% |
| Boiling point | 165-167 °C(lit.) |
| Density | 0.915 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.432(lit.) |
| Storage temperature | 2-8°C |
| Application | Employed in the construction of the key tetrahydropyran subunit in a recent synthesis of the marine natural product (–)-dactylodide.1 |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 60 °C / 140 °F |
| Transport (UN / ADR) | UN 1989C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (tert-Butyldimethylsilyloxy)acetaldehyde used for?
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This compound is primarily used as a building block and intermediate in organic synthesis, particularly in the construction of complex molecules such as natural products.
What are the CAS number and formula for (tert-Butyldimethylsilyloxy)acetaldehyde?
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The CAS number is 102191-92-4, and the linear formula is (CH 3 )3CSi(CH 3 )2OCH 2 CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (tert-Butyldimethylsilyloxy)acetaldehyde with an assay of 90%. We do not represent this product as USP, BP, or EP grade.
How should (tert-Butyldimethylsilyloxy)acetaldehyde be handled safely?
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This compound is flammable and can cause skin, eye, and respiratory irritation (H226, H315, H319, H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Store at 2-8°C.
How is (tert-Butyldimethylsilyloxy)acetaldehyde packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals globally, adhering to all relevant regulations for safe transport.
How can I request a quote or sample?
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To request a quote or sample of (tert-Butyldimethylsilyloxy)acetaldehyde, please contact our sales team through the website or by phone.
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