(±)-1,1,1-Trifluoro-2-butanamine hydrochloride
(±)-1,1,1-Trifluoro-2-butanamine hydrochloride (CAS: 758-33-8) is an organic building block with the empirical formula C4H8F3N · HCl. This trifluoromethylated amine salt is valuable in chemical synthesis due to the unique properties imparted by the fluorine atoms. It is primarily utilized as a reagent and intermediate in the development of novel organic compounds and pharmaceutical research, offering a chiral center for stereoselective applications.
- IUPAC
- 1-(Trifluoromethyl)propylamine hydrochloride
- Synonyms
- 758-33-81-(Trifluoromethyl)propylamine hydrochlorideC4H8F3N · HCl

Organic Synthesis Intermediate
Serves as a versatile building block in the synthesis of complex organic molecules. The trifluoromethyl group can influence lipophilicity and metabolic stability in target compounds.
Pharmaceutical Research
Used in the exploration and development of new active pharmaceutical ingredients (APIs). Its structure can be incorporated to modulate drug properties.
Chiral Chemistry
As a racemic mixture, it can be employed in stereoselective synthesis or resolved into enantiomers for specific chiral applications.
| Empirical formula | C4H8F3N · HCl |
|---|---|
| Assay | ≥96%≥96.0%96.0-104.0% (AT) |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (±)-1,1,1-Trifluoro-2-butanamine hydrochloride used for?
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This compound is primarily used as a building block in organic synthesis and in pharmaceutical research for the development of new compounds.
What is the CAS number and formula for this chemical?
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The CAS number is 758-33-8, and the empirical formula is C4H8F3N · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥96% (AT). This is a technical or research grade, and we do not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should (±)-1,1,1-Trifluoro-2-butanamine hydrochloride be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, face shields, and gloves. It is classified as Danger, with hazards including H301 (Toxic if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).
How is this chemical packed and shipped?
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This chemical is packed and shipped according to international regulations, including UN 2811, Hazard Class 6.1, Packing Group III.
How can I request a sample or quote?
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Please contact our sales department through the website to request a sample or a quotation for (±)-1,1,1-Trifluoro-2-butanamine hydrochloride.
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