(tert-Butoxycarbonylmethyl)triphenylphosphonium chloride
(tert-Butoxycarbonylmethyl)triphenylphosphonium chloride (CAS 35000-37-4) is a chemical reagent with the linear formula (CH3)3COCOCH2P+(C6H5)3Cl and a molecular weight of 412.89 g/mol. This phosphonium salt is primarily employed as a reactant in organic synthesis, particularly for C-C bond formation and olefination reactions. Its utility extends to the stereoselective preparation of complex organic molecules and in thermal decomposition studies.
Stereoselective Synthesis
Serves as a key reactant in the stereoselective preparation of (arylamino)quinazoline derivatives. These compounds are investigated as potential inhibitors of epidermal growth factor receptor and histone deacetylase.
Olefination Reactions
Utilised in Wittig-type reactions for the formation of carbon-carbon double bonds, a fundamental transformation in synthetic organic chemistry.
Thermal Decomposition Studies
Applies to research involving the thermal decomposition mechanisms and characteristics of phosphonium salts.
| Molecular weight | 412.89 |
|---|---|
| Linear formula | (CH3)3COCOCH2P+(C6H5)3Cl |
| Assay | ≥98.0% |
| Application | Reactant for:• Stereoselective preparation of (arylamino)quinazoline derivatives bearing tethered acrylamide moieties as inhibitors of epidermal growth factor receptor and histone deacetylase1• Thermal decomposition reactions2 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (tert-Butoxycarbonylmethyl)triphenylphosphonium chloride used for?
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(tert-Butoxycarbonylmethyl)triphenylphosphonium chloride is used as a reactant in organic synthesis, specifically for C-C bond formation, olefination reactions, stereoselective synthesis of derivatives, and thermal decomposition studies.
What is the CAS number and formula for (tert-Butoxycarbonylmethyl)triphenylphosphonium chloride?
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The CAS number is 35000-37-4, and the linear formula is (CH3)3COCOCH2P+(C6H5)3Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (tert-Butoxycarbonylmethyl)triphenylphosphonium chloride with an assay of ≥98.0%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment includes a dust mask type N95, eyeshields, and gloves. Handle in a well-ventilated area.
How is (tert-Butoxycarbonylmethyl)triphenylphosphonium chloride shipped?
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Tech Serve Solutions exports and ships fine chemicals globally, adhering to all relevant international shipping regulations for hazardous materials.
How can I request a quote or sample?
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To request a quote or sample of (tert-Butoxycarbonylmethyl)triphenylphosphonium chloride, please contact our sales department through the website or provide your details for a prompt response.
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