tert-Butyl trimethylsilylacetate
tert-Butyl trimethylsilylacetate (CAS: 41108-81-0; Formula: C9H20O2Si) is a silicon-containing organic compound with a molecular weight of 188.34 g/mol. It functions as a useful building block and reagent in organic synthesis. Its ester functionality, coupled with the trimethylsilyl group, allows for diverse chemical transformations, making it valuable in research and development settings for constructing more complex molecules.

Organic Synthesis Reagent
Utilised as a building block in the synthesis of various organic compounds. Its chemical structure allows for specific reactions in the development of novel molecules and materials.
Intermediate for Complex Molecules
Serves as an intermediate in multi-step synthetic routes. The ester and silyl functionalities can be selectively manipulated to introduce desired structural features into target compounds.
Research and Development
Employed in academic and industrial research laboratories for exploring new chemical pathways and developing innovative chemical entities. It is a valuable tool for synthetic chemists.
| Molecular weight | 188.34 |
|---|---|
| Empirical formula | C9H20O2Si |
| Assay | ≥95.0% (GC) |
| Boiling point | 67 °C/13 mmHg(lit.) |
| Density | 0.86 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.417n20/D 1.418(lit.) |

Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 42 °C / 107.6 °F |
| Transport (UN / ADR) | UN 3272 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
| Safety statements (S) | 23-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is tert-Butyl trimethylsilylacetate used for?
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tert-Butyl trimethylsilylacetate is primarily used as a building block and reagent in organic synthesis for the construction of complex molecules. It serves as an intermediate in research and development laboratories.
What is the CAS number and formula for tert-Butyl trimethylsilylacetate?
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The CAS number is 41108-81-0, and the empirical formula is C9H20O2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies tert-Butyl trimethylsilylacetate with an assay of ≥95.0% (GC). We do not represent this product as USP, BP, or EP grade.
How should tert-Butyl trimethylsilylacetate be handled safely?
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tert-Butyl trimethylsilylacetate is a flammable liquid and vapour (H226). Handle in a well-ventilated area, away from ignition sources. Recommended personal protective equipment includes eyeshields, face shields, gloves, and appropriate respiratory protection (e.g., type ABEK respirator filter).
Is tert-Butyl trimethylsilylacetate a controlled substance?
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The provided data does not indicate that tert-Butyl trimethylsilylacetate is a controlled substance.
How is tert-Butyl trimethylsilylacetate packed, shipped, and exported?
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As a specialist global supplier, Tech Serve Solutions exports chemicals worldwide. Packing and shipping adhere to international regulations for hazardous materials, including UN 3272, Class 3, Packing Group III.
How can I request a sample or quote for tert-Butyl trimethylsilylacetate?
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To request a sample or a quotation, please contact our sales department through the website or by calling us directly. Our team will be pleased to assist you.
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