Sulfadoxin
Sulfadoxin (CAS: 2447-57-6) is a sulfonamide antibiotic with the molecular formula C12H14N4O4S and a molecular weight of 310.33 g/mol. It is primarily utilized in veterinary medicine and in combination therapies for treating specific parasitic infections, notably malaria caused by <i>Plasmodium falciparum</i>. This compound is also employed in research settings to study infections and their prevention in animal models, playing a role in understanding metabolic pathways related to folic acid.
Antimalarial Therapy
Sulfadoxin, often in combination with pyrimethamine, is indicated for the treatment of <i>Plasmodium falciparum</i> malaria, particularly in regions with known chloroquine resistance. Its mechanism targets essential metabolic pathways in the parasite.
Treatment of Livestock Infections
This sulfonamide antibiotic is also applied in veterinary medicine for managing various infections in livestock. Its broad-spectrum activity aids in controlling bacterial and parasitic diseases affecting farm animals.
Research and Development
Sulfadoxin is used in laboratory settings to study infections such as those caused by <i>Toxoplasma gondii</i> and to investigate preventative strategies in animal models. It serves as a valuable tool in biochemical and cell biology research.
| Molecular weight | 310.33 |
|---|---|
| Empirical formula | C12H14N4O4S |
| Assay | ≥95% (TLC) |
| Application | Sulfadoxine is a sulfonamide antibiotic used in combination with pyrimethamine for the treatment or prevention of malaria. It is also used to treat various infections in livestock. Sulfadoxine and pyrimethamine is indicated for the treatment of Plasmodium falciparum malaria in patients where chloroquine resistance is suspected1. It is used to study infections caused by Toxoplasma gondii2 and has been used to prevent infections after surgery during animal studies3. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sulfadoxin used for?
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Sulfadoxin is primarily used in combination with pyrimethamine for treating malaria caused by <i>Plasmodium falciparum</i>, especially where chloroquine resistance is present. It is also used in veterinary medicine for infections in livestock and in research for studying various infections and their prevention.
What is the CAS number and molecular formula for Sulfadoxin?
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Sulfadoxin has the CAS number 2447-57-6 and its molecular formula is C12H14N4O4S.
What grade and purity does Tech Serve Solutions supply for Sulfadoxin?
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Tech Serve Solutions supplies Sulfadoxin with a purity of ≥95% (TLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Sulfadoxin be handled safely?
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Sulfadoxin is a warning-level chemical that can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). When handling, use a dust mask type N95 (US), wear eyeshields, and use gloves. Ensure adequate ventilation.
Is Sulfadoxin a controlled substance?
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The provided data does not indicate that Sulfadoxin is a controlled substance.
How is Sulfadoxin packed and shipped?
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Sulfadoxin is carefully packed to ensure integrity during transit. As a global supplier and exporter, Tech Serve Solutions adheres to all relevant shipping regulations for chemical compounds.
How can I request a sample or quote for Sulfadoxin?
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To request a sample or a quote for Sulfadoxin, please contact our sales department through the details provided on our website.
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