Sulfadimidine solution

CAS 57-68-1C12H14N4O2SBiochemicals & Reagents

Sulfadimidine solution (CAS 57-68-1, C12H14N4O2S) is a chemical compound with a molecular weight of 278.33 g/mol. It is primarily utilized in research for its properties as an inducer of cytochrome P450 3A4 (CYP3A4) and an inhibitor of dihydrofolate reductase (DHFR). This compound aids in the study of various biochemical pathways and drug metabolism.

IUPAC: 4,6-Dimethylsulfadiazine,4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide,Sulfadimethyldiazine,Sulfadimidine
Synonyms: 4,6-Dimethylsulfadiazine4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamideSulfadimethyldiazineSulfadimidine

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Sulfadimidine solution (C12H14N4O2S) — chemical structure, CAS 57-68-1; Life Science, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Cytochrome P450 3A4 Induction Studies

Sulfadimidine is employed in laboratory settings to induce the activity of cytochrome P450 3A4 (CYP3A4). This application is crucial for researchers investigating drug metabolism and potential drug-drug interactions.

Dihydrofolate Reductase (DHFR) Inhibition Research

The compound serves as an inhibitor of dihydrofolate reductase (DHFR). This function is valuable for studies focused on cellular processes dependent on folate metabolism and antimicrobial mechanisms.

Amantadine Acetylation Studies

Historically, Sulfadimidine has been used in specific research contexts to investigate the acetylation pathways of compounds like amantadine, contributing to a deeper understanding of biochemical transformations.

02 /Properties

Molecular weight	278.33
Empirical formula	C12H14N4O2S
Assay	≥99%
Concentration	1 mg/mL in H2O
Application	Sulfadimidine is used to induce cytochrome P450 3A4 (CYP3A4) 1 and to inhibit dihydrofolate reductase (DHFR). It has been used to study amantadine acetylation 2.
Suitability	suitable for 1694 per US EPA

03 /Safety & handling

Protective equipment	Eyeshields, Gloves
Water hazard class (WGK, DE)	nwg

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

57-68-1

MDL number

MFCD00006066

Beilstein registry

261304

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Sulfadimidine solution used for?

Sulfadimidine solution is used in research to induce cytochrome P450 3A4 (CYP3A4) and to inhibit dihydrofolate reductase (DHFR). It has also been used to study amantadine acetylation.

What are the CAS number and formula for Sulfadimidine solution?

The CAS number for Sulfadimidine solution is 57-68-1, and its empirical formula is C12H14N4O2S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Sulfadimidine solution with an assay of ≥99%. It is suitable for research purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety and handling precautions for Sulfadimidine solution?

When handling Sulfadimidine solution, it is recommended to use safety measures such as eyeshields and gloves. Always consult the Safety Data Sheet (SDS) for comprehensive handling information.