Sulfadiazine
Sulfadiazine (CAS: 68-35-9), with the empirical formula C10H10N4O2S and a molecular weight of 250.28, is a short-acting sulfonamide antibiotic. It is primarily employed in combination with pyrimethamine for treating toxoplasmosis, particularly in individuals with compromised immune systems like those with AIDS. It is also utilised for managing congenital infections in newborns and in research for controlling reactivated toxoplasmosis in murine models. Tech Serve Solutions supplies Sulfadiazine with an assay of ≥99.0%.
- IUPAC
- 4-Amino-N-(2-pyrimidinyl)benzenesulfonamide,N1-(Pyrimidin-2-yl)sulfanilamide
- Synonyms
- 4-Amino-N-(2-pyrimidinyl)benzenesulfonamide, N1-(Pyrimidin-2-yl)sulfanilamide
Treatment of Toxoplasmosis
Sulfadiazine is a key component, used alongside pyrimethamine, for managing toxoplasmosis. This is especially critical for patients with weakened immune systems, such as those affected by AIDS.
Congenital Infections in Newborns
This sulfonamide is also administered to newborns to treat congenital infections, providing essential early-stage treatment for vulnerable infants.
Research in Murine Models
In laboratory settings, Sulfadiazine is used to control acute infections within murine models, specifically for studying reactivated toxoplasmosis.
| Molecular weight | 250.28 |
|---|---|
| Empirical formula | C10H10N4O2S |
| Assay | ≥99.0% |
| Application | Sulfadiazine is a short-acting sulfonamide that is commonly used with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome. It is also used to treat newborns with congenital infections1. Sulfadiazine has been used to control acute infections when studying murine models of reactivated toxoplasmosis2. |
| Melting point | 253 °C (dec.)(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-42/43 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sulfadiazine used for?
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Sulfadiazine is used to treat toxoplasmosis in immunocompromised individuals, congenital infections in newborns, and in murine models for research into reactivated toxoplasmosis.
What are the CAS number and formula for Sulfadiazine?
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The CAS number for Sulfadiazine is 68-35-9, and its empirical formula is C10H10N4O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sulfadiazine with a minimum assay of ≥99.0%. We do not represent this product as USP, BP, or EP grade.
What are the primary safety concerns when handling Sulfadiazine?
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Sulfadiazine is classified with Danger signal word, presenting hazards including H302 (Harmful if swallowed), H315 (Causes skin irritation), H317 (May cause an allergic skin reaction), H319 (Causes serious eye irritation), H334 (May cause allergy or asthma symptoms or breathing difficulties if inhaled), and H335 (May cause respiratory irritation). Appropriate PPE including dust mask, eyeshields, face shields, and gloves is essential.
How is Sulfadiazine packed, shipped, and exported?
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Tech Serve Solutions handles the packing, shipping, and international export of Sulfadiazine with adherence to all necessary regulations, ensuring safe and compliant delivery globally.
How can I request a sample or quote for Sulfadiazine?
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To request a sample or a quote for Sulfadiazine, please contact our sales team directly through our website or by phone.
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