YC-1
YC-1 (CAS: 170632-47-0; Formula: C19H16N2O2; MW: 304.34 g/mol) is a white solid chemical compound. It is recognised as a potent and selective activator of soluble guanylyl cyclase (sGC), a key enzyme in the nitric oxide signalling pathway. YC-1 is widely utilised in biochemical and pharmacological research to investigate the physiological roles of cyclic GMP (cGMP) and its downstream effects in various biological systems, including cardiovascular and neurological functions.
- IUPAC
- 3-(5′-Hydroxymethyl-2′-furyl)-1-benzyl indazole

Guanylyl Cyclase Activation
YC-1 acts as a powerful activator of soluble guanylyl cyclase (sGC). This makes it an invaluable tool for studying the NO-sGC-cGMP signalling cascade in various cellular and physiological contexts.
Cellular Signalling Research
Researchers employ YC-1 to probe the intricate mechanisms of cell signalling pathways, particularly those involving cyclic nucleotides like cGMP. Its specific action aids in understanding cellular responses to stimuli.
Neuroscience Investigations
The compound is used in neuroscience research to explore the role of sGC and cGMP in neuronal function, neurotransmission, and potential therapeutic targets for neurological disorders.
Cardiovascular Studies
YC-1's mechanism of action is relevant to cardiovascular research, aiding in the study of vasodilation, blood pressure regulation, and related physiological processes influenced by the NO pathway.
| Molecular weight | 304.34 |
|---|---|
| Empirical formula | C19H16N2O2 |
| Form | solid |
| Colour | white |
| Solubility | DMSO: soluble10 mg/mLH2O: insoluble |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PDE5A(8654) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is YC-1 used for?
+
YC-1 is used as a potent and selective activator of soluble guanylyl cyclase (sGC) for research purposes, particularly in studying the nitric oxide signalling pathway, cyclic GMP metabolism, and related cellular and physiological functions.
What is the CAS number and chemical formula for YC-1?
+
The CAS number for YC-1 is 170632-47-0, and its empirical formula is C19H16N2O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies YC-1 as a research-grade chemical. The specific purity is not stated in the provided data, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for YC-1?
+
When handling YC-1, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a WGK Germany classification of 3, indicating it is hazardous to water.
How is YC-1 packed and shipped?
+
YC-1 is typically supplied as a white solid. Specific packing and shipping details are available upon request. Tech Serve Solutions is a global exporter of fine chemicals.
How can I request a sample or quote for YC-1?
+
To request a sample or a quote for YC-1, please contact the Tech Serve Solutions sales team through our official channels.
▶ Related products

(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology

(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology

(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology

(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis