Xylometazoline hydrochloride
Xylometazoline hydrochloride (CAS: 1218-35-5), with the molecular formula C16H24N2 · HCl and a molecular weight of 280.84 g/mol, is an imidazoline derivative. It functions as an alpha-adrenergic agonist, primarily recognised for its vasoconstrictive properties. This compound is widely utilised in pharmaceutical formulations for its efficacy in nasal decongestants, helping to alleviate symptoms associated with colds, allergies, and sinusitis by reducing swelling in the nasal passages. It is a key ingredient in many over-the-counter and prescription medications.
- IUPAC
- 2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride
Nasal Decongestant Formulations
Xylometazoline hydrochloride is a principal active pharmaceutical ingredient in nasal sprays and drops designed to provide temporary relief from nasal congestion. Its vasoconstrictive action reduces swelling of the nasal mucosa.
Ophthalmic Preparations
In some ophthalmic solutions, it may be used for its vasoconstrictive effects to reduce redness and swelling in the eyes, though this application is less common than its nasal use.
Research and Development
As a well-characterised adrenergic agonist, it serves as a valuable tool in pharmacological research, particularly in studies related to alpha-adrenergic receptor function and neurotransmission.
| Molecular weight | 280.84 |
|---|---|
| Empirical formula | C16H24N2 · HCl |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Xylometazoline hydrochloride used for?
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Xylometazoline hydrochloride is primarily used as a nasal decongestant to relieve stuffy noses caused by colds, allergies, or sinusitis. It works by constricting blood vessels in the nasal passages, reducing swelling and making breathing easier.
What is the CAS number and chemical formula for Xylometazoline hydrochloride?
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The CAS number for Xylometazoline hydrochloride is 1218-35-5, and its chemical formula is C16H24N2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Xylometazoline hydrochloride for research and development purposes. The specific assay and grade available are detailed on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade unless explicitly stated in the product documentation.
How should Xylometazoline hydrochloride be handled safely?
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Xylometazoline hydrochloride is classified as toxic if swallowed (H301) and requires careful handling. Use appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, face shields, and gloves. Ensure adequate ventilation and avoid ingestion, inhalation, or skin contact. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is Xylometazoline hydrochloride a controlled substance?
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Based on the provided data, Xylometazoline hydrochloride is not listed as a controlled substance. However, regulations can vary by jurisdiction, and it is the user's responsibility to ensure compliance with local laws.
How can I request a sample or quote for Xylometazoline hydrochloride?
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To request a sample or a quote for Xylometazoline hydrochloride, please contact our sales department through the website or by phone. Our team will be happy to assist you with your inquiry.
How is Xylometazoline hydrochloride packed and shipped?
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Xylometazoline hydrochloride is packed according to relevant transport regulations, including UN 2811 classification for toxic solids. TSS exports fine chemicals globally, ensuring compliance with international shipping standards.
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