YM-58483
YM-58483 (CAS: 223499-30-7), a fluorinated thiadiazole derivative with the empirical formula C15H9F6N5OS and a molecular weight of 421.32 g/mol, is supplied as a white solid. This compound serves as a valuable research tool in cell biology and neuroscience, specifically for investigating calcium channel modulators and voltage-gated ion channels. Its inhibitory and activating properties make it useful for studying cellular signalling pathways.
- IUPAC
- 4-methyl-4′-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]-1,2,3-thiadiazole-5-carboxanilide

Calcium Channel Modulation Research
YM-58483 is utilised to investigate the function and regulation of calcium channels. It helps researchers understand the complex mechanisms of ion transport and its role in cellular processes.
Neuroscience and Cell Signaling Studies
This compound is employed as a tool in neuroscience and cell signaling research. It aids in elucidating the pathways involved in neuronal communication and other cellular responses.
Ion Channel Investigations
YM-58483 facilitates studies on various ion channels, including voltage-gated types. Researchers use it to probe channel activity and pharmacology, contributing to a deeper understanding of physiological functions.
| Molecular weight | 421.32 |
|---|---|
| Empirical formula | C15H9F6N5OS |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | 2-8°C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is YM-58483 primarily used for?
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YM-58483 is primarily used as a research chemical for investigating calcium channel modulation, cell signaling, neuroscience, and ion channel function.
What is the CAS number and chemical formula for YM-58483?
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The CAS number for YM-58483 is 223499-30-7, and its empirical formula is C15H9F6N5OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies YM-58483 with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for YM-58483?
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YM-58483 is classified with a Warning signal word and carries hazard statements H302, H315, H319, and H335, indicating it is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is YM-58483 typically stored and shipped?
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YM-58483 should be stored at 2-8°C. Tech Serve Solutions can export this product globally, adhering to all relevant shipping regulations.
How can I request a quote or sample for YM-58483?
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To request a quote or sample for YM-58483, please contact our sales team through the website or provide your details via the contact form.
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