Strychnine hydrochloride
Strychnine hydrochloride (CAS: 1421-86-9), with the molecular formula C21H22N2O2 · HCl and a molecular weight of 370.87 g/mol, is a highly toxic alkaloid salt. It functions as a potent antagonist of glycine and GABA receptors. Primarily utilized in scientific research, it serves as a valuable tool for investigating neuronal pathways and receptor function, particularly within neuroscience and cell biology studies.

Neuroscience Research
Strychnine hydrochloride is widely employed as a selective antagonist of glycine receptors. This makes it indispensable for studying inhibitory neurotransmission, neuronal excitability, and the function of specific ion channels in the central nervous system.
Cell Biology Studies
Its specific action on neurotransmitter receptors allows researchers to probe cellular signaling pathways. It is used to understand the role of inhibitory neurotransmitters in various cellular processes and responses.
Pharmacological Tool
As a well-characterised ligand-gated ion channel modulator, it serves as a critical reference compound in drug discovery and development for neurological disorders. It aids in the characterisation of novel therapeutic targets.
| Molecular weight | 370.87 |
|---|---|
| Empirical formula | C21H22N2O2 · HCl |


Hazard statements
- H300Fatal if swallowed
- H330Fatal if inhaled
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P273Avoid release to the environment
- P284Wear respiratory protection
- P301IF SWALLOWED
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1692 6.1/PG 1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+,N |
| Risk statements (R) | 26/28-50/53 |
| Safety statements (S) | 13-28-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Strychnine hydrochloride primarily used for?
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Strychnine hydrochloride is primarily used in scientific research as a selective antagonist for glycine receptors, aiding investigations into neuroscience, cell biology, and neuronal signaling.
What are the CAS number and chemical formula for Strychnine hydrochloride?
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The CAS number for Strychnine hydrochloride is 1421-86-9, and its chemical formula is C21H22N2O2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Strychnine hydrochloride typically as a research or technical grade chemical. We do not represent it as USP, BP, or EP grade unless explicitly stated otherwise.
How should Strychnine hydrochloride be handled safely?
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Strychnine hydrochloride is highly toxic (Danger, H300-H330-H410) and requires extreme caution. Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Handle only in well-ventilated areas and avoid any exposure.
Is Strychnine hydrochloride a controlled substance?
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While the provided data does not explicitly state its controlled substance status, Strychnine hydrochloride is an extremely toxic substance and its handling, possession, and use may be subject to strict regulations in many jurisdictions due to its toxicity.
How is Strychnine hydrochloride packed, shipped, and exported?
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Strychnine hydrochloride is carefully packed according to international shipping regulations for hazardous materials. TSS is an experienced global exporter and can manage the complexities of shipping this product worldwide.
How can I request a sample or quote for Strychnine hydrochloride?
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To request a sample or a quotation for Strychnine hydrochloride, please contact our sales team through the website or by calling us directly. Provide your details and the quantity required.
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