SQ 22,536
SQ 22,536 (CAS: 17318-31-9), with the molecular formula C9H11N5O and a molecular weight of 205.22 g/mol, is a chemical compound recognised for its role as an adenylyl cyclase inhibitor. This white to off-white powder is primarily utilised in biochemical research for investigating cellular processes. Its applications extend to studying cell differentiation and intercellular communication, making it a valuable reagent for cell biology and neuroscience research.
- IUPAC
- 9-(Tetrahydro-2-furanyl)-9H-purin-6-amine,9-THF-Ade
- Synonyms
- 9-(Tetrahydro-2-furanyl)-9H-purin-6-amine9-THF-Ade

Cellular Differentiation Studies
SQ 22,536 has been employed in research to investigate the role of adenylate cyclase in the differentiation of PC12 cells, contributing to the understanding of neuronal development and cell fate determination.
Intercellular Communication Research
This compound has been used to study the impact of adenylyl cyclase inhibition on gap junctional intercellular communication, particularly within the context of breast cancer cell behaviour.
Biochemical Research Reagent
As a well-characterised adenylyl cyclase inhibitor, SQ 22,536 serves as a crucial tool for researchers exploring cyclic nucleotide metabolism and signal transduction pathways in various biological systems.
| Molecular weight | 205.22 |
|---|---|
| Empirical formula | C9H11N5O |
| Assay | ≥97% (HPLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | DMSO: >10 mg/mLH2O: >10 mg/mL |
| Application | SQ 22,536 was used to study the role of adenylate cyclase in differentiation of PC12 cells1 and in gap junctional intercellular communication in breast cancer cells.2 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SQ 22,536 primarily used for?
+
SQ 22,536 is primarily used in biochemical and cellular research as an adenylyl cyclase inhibitor to study processes such as cell differentiation and intercellular communication.
What is the CAS number and molecular formula for SQ 22,536?
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The CAS number for SQ 22,536 is 17318-31-9, and its molecular formula is C9H11N5O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SQ 22,536 with a purity of ≥97% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should SQ 22,536 be handled safely?
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SQ 22,536 is a Warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). When handling, wear a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.
How is SQ 22,536 shipped and exported?
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SQ 22,536 is available for purchase and can be shipped and exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.
How can I request a sample or quote for SQ 22,536?
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To request a sample or quote for SQ 22,536, please contact our sales department through the website or by calling our office.
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