SR 27417

CAS 136468-36-5C28H40N4SCell Biology

SR 27417 (CAS: 136468-36-5, C28H40N4S) is a potent, selective, and orally bioavailable antagonist of the platelet-activating factor (PAF) receptor. This white to beige powder, with a molecular weight of 464.71, is crucial in cell signalling research. Its primary applications lie in investigating cellular responses mediated by PAF, contributing to advancements in cell biology, neuroscience, and lipid signalling studies.

IUPAC: Faropafant,N,N-Dimethyl-N′-(3-pyridinylmethyl)-N′-[4-[2,4,6-tris(1-methylethyl)phenyl]-2-thiazolyl]-1,2-ethanediamine,N1,N1-Dimethyl-N2-(3-pyridinylmethyl)-N2-[4-[2,4,6-tris(1-methylethyl)phenyl]-2-thiazolyl]-1,2-ethanediamine

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SR 27417 (C28H40N4S) — chemical structure, CAS 136468-36-5; Life Science, fine chemical supplied by Tech Serve Solutions

Cell BiologyLipids in Cell SignalingPlatelet Activating Factors

01 /Applications

Platelet-Activating Factor Receptor Antagonism

SR 27417 serves as a key research tool for blocking the effects of Platelet-Activating Factor (PAF) by selectively inhibiting its receptor. This enables detailed studies into PAF-mediated inflammatory and allergic responses.

Cell Signalling and Neuroscience Research

As a modulator of cell signalling pathways involving lipids, SR 27417 is utilised in neuroscience to explore the role of PAF in neuronal function and pathology. Its applications extend to understanding lipid-based intercellular communication.

Investigating Inflammatory Processes

The compound's ability to antagonise the PAF receptor makes it invaluable for research into inflammatory conditions where PAF plays a significant role. This includes studying conditions like asthma and other allergic reactions.

02 /Properties

Molecular weight	464.71
Empirical formula	C28H40N4S
Assay	≥98% (HPLC)
Form	powder
Colour	white to beige
Solubility	DMSO: soluble5 mg/mL (clear solution, warmed)
Storage temperature	2-8°C

03 /Identifiers & registry

CAS number

136468-36-5

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is SR 27417 used for?

SR 27417 is used as a selective and orally bioavailable antagonist of the platelet-activating factor (PAF) receptor, primarily for research in cell biology, cell signalling, neuroscience, and the study of lipids in cell signalling.

What are the CAS number and formula for SR 27417?

The CAS number for SR 27417 is 136468-36-5, and its molecular formula is C28H40N4S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies SR 27417 with a purity of ≥98% (HPLC). This is a research-grade chemical, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.

How should SR 27417 be handled and stored?

SR 27417 is classified under GHS07 and GHS09, indicating potential skin, eye, and respiratory irritation, and environmental hazards. It should be handled with appropriate personal protective equipment in a well-ventilated area. Recommended storage is at 2-8°C.

Is SR 27417 available for export?

Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including SR 27417. We can facilitate international shipments according to regulatory requirements.

How can I request a sample or quote for SR 27417?

To request a sample or a quote for SR 27417, please visit the product page on our website or contact our sales team directly with your specific requirements.