1,2,3,4-Tetrahydroharmane-3-carboxylic acid

CAS 5470-37-1C13H14N2O2Chemical Synthesis

1,2,3,4-Tetrahydroharmane-3-carboxylic acid (CAS: 5470-37-1) is an organic compound with the molecular formula C13H14N2O2 and a molecular weight of 230.26 g/mol. It serves as a valuable building block in chemical synthesis, particularly for generating molecules relevant to biological studies. Its applications span the synthesis of various biologically active derivatives and heterocyclic compounds.

IUPAC: 1-Methyl-1,2,3,4-Tetrahydropyrido[3,4-b]indole-3-carboxylic acid,1-Methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid,NSC 26225
Synonyms: 4-Tetrahydroharmane-3-carboxylic acid1-Methyl-1,2,3,4-Tetrahydropyrido[3,4-b]indole-3-carboxylic acid1-Methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acidNSC 26225

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1,2,3,4-Tetrahydroharmane-3-carboxylic acid (C13H14N2O2) — chemical structure, CAS 5470-37-1; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksC13 to C42+Carbonyl CompoundsCarboxylic AcidsChemical Synthesis

01 /Applications

Synthesis of Harmine Derivatives

This compound is utilized as a reactant in the synthesis of harmine derivatives, which have been investigated for their cytotoxicity and insecticidal activities. This highlights its role in medicinal chemistry research.

Preparation of Isoquinolines and β-Carbolines

It is employed in oxidative decarboxylation reactions to prepare important heterocyclic structures such as isoquinolines, β-carbolines, and 3-deazapurines. These structures are often of interest in pharmaceutical research.

Cytotoxic Compound Synthesis

The compound participates in the synthesis of 1,3-di- and 1,3,9-trisubstituted β-carbolines, which are then evaluated for their cytotoxic properties. This application underscores its utility in drug discovery programmes.

02 /Properties

Molecular weight	230.26
Empirical formula	C13H14N2O2
Storage temperature	−20°C
Application	Reactant involved in synthesis of molecules for biological studies including:• Cytotoxicity and insecticidal activities of harmine derivatives1• Isoquinolines, β-carbolines, and 3-deazapurines via oxidative decarboxylation2• Cytotoxic evaluation of 1,3-di- and 1,3,9-trisubstituted β-carbolines3

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

5470-37-1

MDL number

MFCD00022199

PubChem substance

24895402

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1,2,3,4-Tetrahydroharmane-3-carboxylic acid used for?

1,2,3,4-Tetrahydroharmane-3-carboxylic acid is used as a building block in chemical synthesis, primarily for the preparation of molecules studied for biological activities, including cytotoxicity and insecticidal properties, as well as for synthesizing various heterocyclic compounds like β-carbolines.

What is the CAS number and molecular formula?

The CAS number is 5470-37-1 and the molecular formula is C13H14N2O2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical as a building block for research purposes. The specific grade and purity will be detailed on the Certificate of Analysis for the batch supplied. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should 1,2,3,4-Tetrahydroharmane-3-carboxylic acid be handled?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK 2 in Germany, indicating a moderate hazard to water.

How is this product shipped?

As a global supplier and exporter, Tech Serve Solutions ships fine chemicals worldwide, adhering to all necessary regulations for safe and compliant transport.

How can I request a sample or quote?

To request a sample or quote for 1,2,3,4-Tetrahydroharmane-3-carboxylic acid, please use the contact form on our website or contact our sales department directly.