1,2,3,4-Tetrahydroisoquinoline
1,2,3,4-Tetrahydroisoquinoline (CAS: 91-21-4; C9H11N) is a nitrogen-containing heterocyclic organic compound with a molecular weight of 133.19 g/mol. This chemical serves as a valuable building block in organic synthesis and is utilised in research settings for the development of novel compounds. Its structure is foundational for various biologically active molecules, making it a key intermediate in chemical research and development.
- Synonyms
- 4-Tetrahydroisoquinoline1,2,3,4-Tetrahydroisoquinoline

Chemical Synthesis Intermediate
1,2,3,4-Tetrahydroisoquinoline is employed as a versatile building block in the synthesis of more complex organic molecules. Its heterocyclic structure is a key feature in the development of various research chemicals.
Research and Development
Utilised in laboratory settings for exploring new chemical pathways and creating novel compounds. It is particularly relevant in fields investigating bioactive small molecules and heterocycles.
Pharmaceutical Intermediate
Serves as a precursor or intermediate in the multi-step synthesis of potential pharmaceutical agents and drug candidates, due to its isoquinoline core.
| Molecular weight | 133.19 |
|---|---|
| Empirical formula | C9H11N |
| Assay | 95% |
| Boiling point | 232-233 °C(lit.) |
| Density | 1.064 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.568(lit.) |
| Melting point | −30 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 99 °C / 210.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PNMT(5409)rat ... Adra2a(25083), Htr1a(24473) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2,3,4-Tetrahydroisoquinoline used for?
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1,2,3,4-Tetrahydroisoquinoline is primarily used as a chemical synthesis intermediate and in research and development for creating novel compounds and exploring new chemical pathways. It is also relevant in the synthesis of bioactive small molecules and potential pharmaceutical agents.
What are the CAS number and formula for 1,2,3,4-Tetrahydroisoquinoline?
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The CAS number for 1,2,3,4-Tetrahydroisoquinoline is 91-21-4, and its empirical formula is C9H11N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2,3,4-Tetrahydroisoquinoline with a minimum assay of 95%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the safety considerations when handling 1,2,3,4-Tetrahydroisoquinoline?
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1,2,3,4-Tetrahydroisoquinoline is a Warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be used. Ensure adequate ventilation and use a suitable respirator cartridge when handling.
How is 1,2,3,4-Tetrahydroisoquinoline packed and shipped?
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Tech Serve Solutions carefully packs and exports chemicals in compliance with all relevant shipping regulations. Specific packaging details are available upon request for export orders.
How can I request a sample or quote for 1,2,3,4-Tetrahydroisoquinoline?
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To request a sample or a quote for 1,2,3,4-Tetrahydroisoquinoline, please contact our sales team through the website or provide your details via the 'Enquire' button.
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