Sodium (meta)periodate
Sodium (meta)periodate (CAS 7790-28-5) is a powerful oxidizing agent with the chemical formula NaIO4. It is supplied by TSS as a high-purity PREMIUM grade reagent, suitable for various laboratory and industrial applications. Primarily, it is recognised for its utility in organic synthesis, particularly for the selective oxidation of vicinal diols and in the detection of glycoproteins through biotin labeling in biochemical research.
- IUPAC
- Sodium (meta)periodate
Oxidation in Organic Synthesis
Sodium (meta)periodate serves as a key reagent for the oxidative cleavage of carbon-carbon bonds, particularly in vicinal diols, yielding aldehydes or carboxylic acids. Its controlled reactivity makes it valuable in multi-step synthesis pathways.
Biochemical Labeling and Detection
This compound is instrumental in preparing biotin-labeled carbohydrates for assays. It oxidises saccharides, creating aldehyde functional groups that react with biotin hydrazide, facilitating detection of glycoproteins in techniques like Western blotting.
Chemical Synthesis Reagent
As a versatile oxidizing agent, Sodium (meta)periodate finds use in various chemical synthesis procedures requiring precise control over oxidation states. Its high purity ensures reliable and reproducible reaction outcomes.
| Molecular weight | 213.89 |
|---|---|
| Linear formula | NaIO4 |
| Assay | ≥99.8%99.8-100.3% dry basis (ACS specification) |
| Solubility | H2O: soluble50 mg/mL |
| Concentration | 10 wt. % |
| Impurities tested | ≤0.02% other halogens (as Cl) |
| Application | Useful reagent for the oxidation of carbohydrates prior to labeling with biotin hydrazide |
| Melting point | 300 °C (dec.)(lit.) |
Hazard statements
- H272May intensify fire; oxidiser
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P220Keep away from clothing and combustible materials
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3087 5.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | O,Xn |
| Risk statements (R) | 8-22-36/37/38 |
| Safety statements (S) | 26 |
| Cation traces | Mn: ≤3 ppm |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|---|
| Matrix | silica gel support |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sodium (meta)periodate used for?
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Sodium (meta)periodate is primarily used as an oxidizing agent in organic synthesis, including the cleavage of vicinal diols. It is also employed in biochemical applications for the detection of biotin-labeled glycoproteins on Western blots.
What are the CAS number and chemical formula for Sodium (meta)periodate?
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The CAS number for Sodium (meta)periodate is 7790-28-5, and its chemical formula is NaIO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sodium (meta)periodate in PREMIUM grade, with an assay of ≥99.8% (dry basis, ACS specification). TSS does not represent this product as USP, BP, or EP grade.
How should Sodium (meta)periodate be handled safely?
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Sodium (meta)periodate is an oxidizer and is harmful if swallowed; it causes skin and eye irritation and may cause respiratory irritation. Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and handle in a well-ventilated area. Refer to the Safety Data Sheet for detailed information.
How is Sodium (meta)periodate packed, shipped, and exported?
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Tech Serve Solutions offers Sodium (meta)periodate in various pack sizes, adhering to all relevant regulations for safe packaging, shipping, and international export of chemicals.
How can I request a quote or sample of Sodium (meta)periodate?
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To request a quote or a sample of Sodium (meta)periodate, please contact the TSS sales team through our website or by phone, providing your specific requirements.
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