SEW2871
SEW2871 (CAS: 256414-75-2) is a bioactive small molecule with the empirical formula C20H10F6N2OS and a molecular weight of 440.36 g/mol. This compound is primarily utilized in biochemical research to mimic the effects of sphingosine-1-phosphate, enabling studies into cellular signaling pathways and innate immunity. It is supplied as a white solid with high purity, suitable for advanced laboratory applications.
- IUPAC
- 5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]- 1,2,4-oxadiazole
Biochemical Research
SEW2871 serves as a valuable tool for researchers investigating the biological roles of sphingolipids. It can mimic the actions of sphingosine-1-phosphate, aiding in the study of cellular responses and pathways.
Cellular Signaling Studies
This compound is used to probe cellular signaling mechanisms, particularly in relation to innate immunity. Its ability to emulate sphingosine-1-phosphate effects allows for detailed analysis of signal transduction.
Innate Immunity Research
SEW2871 has been employed in studies examining the mechanisms of innate immunity, specifically how long pentraxin 3 contributes to these processes. Research has involved its effects on human umbilical vein endothelial cells (HUVECs).
| Molecular weight | 440.36 |
|---|---|
| Empirical formula | C20H10F6N2OS |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: ≥10 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Melting point | 94.5-95.3 °C |
| Application | SEW2871 was used to mimic the effects of spingosine-1 phosphate in HUVECs to study the innate immunity rendered by long pentraxin 3.1 |
Hazard statements
- H300Fatal if swallowed
Precautionary statements
- P264Wash thoroughly after handling
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... S1PR1(1901), S1PR2(9294), S1PR3(1903), S1PR4(8698), S1PR5(53637) |
|---|---|
| Storage Condition | protect from light |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SEW2871 used for?
+
SEW2871 is used in biochemical research to mimic the effects of sphingosine-1-phosphate, aiding in the study of cellular signaling and innate immunity.
What are the CAS number and formula for SEW2871?
+
The CAS number for SEW2871 is 256414-75-2, and its empirical formula is C20H10F6N2OS.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies SEW2871 with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should SEW2871 be handled safely?
+
SEW2871 is classified as Danger (GHS06) and carries the hazard statement H300 (Fatal if swallowed). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges, must be used. Handle with extreme caution to avoid ingestion.
How is SEW2871 packed, shipped, and exported?
+
SEW2871 is packed, shipped, and exported by TSS in compliance with all relevant regulations for hazardous materials. It is shipped as a solid and requires storage at 2-8°C, protected from light.
How can I request a sample or quote for SEW2871?
+
To request a sample or a quote for SEW2871, please contact the Tech Serve Solutions sales department via our website or direct inquiry channels.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis