SDZ 220-581 hydrochloride
SDZ 220-581 hydrochloride (CAS: 179411-93-9) is a chemical compound supplied by Tech Serve Solutions. Its empirical formula is C16H17ClNO5P · HCl. This white to beige powder is primarily utilized in research settings, particularly within cell biology, cell signaling, neuroscience, and ion channel studies. It serves as a valuable tool for investigating excitatory amino acid pathways and as an NMDA antagonist, contributing to a deeper understanding of neurotransmission and related neurological processes.
- IUPAC
- (S)-α-Amino-2-chloro-5-(phosphonomethyl)[1,1-biphenyl]-3-propanoic acid hydrochloride

Neuroscience Research
SDZ 220-581 hydrochloride is employed in neuroscience research to investigate the function of neurotransmitter systems, particularly those involving glutamate receptors. Its properties as an NMDA antagonist make it a useful tool for studying excitotoxicity and neuronal signalling pathways.
Ion Channel Modulation Studies
This compound is valuable for research into ion channels, specifically ligand-gated ion channels. It helps researchers understand the mechanisms by which these channels are modulated and their role in cellular communication.
Cell Signaling Pathways
As a modulator of excitatory amino acid pathways, SDZ 220-581 hydrochloride aids in the study of complex cell signaling cascades. This is crucial for understanding normal physiological processes and the pathophysiology of neurological disorders.
| Empirical formula | C16H17ClNO5P · HCl |
|---|---|
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble5 mg/mL, clear (warmed) |
| Optical activity | [α]/D -5 to -8°, c = 1 in 1 M HCl |
| Storage temperature | room temp |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SDZ 220-581 hydrochloride used for?
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SDZ 220-581 hydrochloride is used in scientific research, particularly in fields such as cell biology, neuroscience, and ion channel studies. It is recognised for its role in investigating excitatory amino acid pathways and as an NMDA antagonist.
What is the CAS number and formula for SDZ 220-581 hydrochloride?
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The CAS number for SDZ 220-581 hydrochloride is 179411-93-9. The empirical formula is C16H17ClNO5P · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SDZ 220-581 hydrochloride with a purity of ≥98% (HPLC). This product is intended for research and laboratory use. Tech Serve Solutions does not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards unless explicitly stated.
How should SDZ 220-581 hydrochloride be handled safely?
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SDZ 220-581 hydrochloride is classified as a warning substance. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing dust. In case of contact with eyes, rinse cautiously with water for several minutes and seek medical advice.
Is SDZ 220-581 hydrochloride a controlled substance?
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The provided data does not indicate that SDZ 220-581 hydrochloride is a controlled substance.
How is SDZ 220-581 hydrochloride shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of shipping and exporting SDZ 220-581 hydrochloride to research institutions worldwide. Please contact us for specific shipping and export inquiries.
How can I request a sample or quote for SDZ 220-581 hydrochloride?
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To request a sample or a quote for SDZ 220-581 hydrochloride, please visit the Tech Serve Solutions website or contact our sales team directly. Our team will be pleased to assist you with your inquiry.
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