SD-208
SD-208 (CAS: 627536-09-8) is a chemical compound with a molecular weight of 352.75 g/mol. It is supplied as an off-white to tan powder with a purity of ≥98% (HPLC). This compound is primarily utilised in biological research, specifically for inhibiting ALK5 kinase activity in cellular studies, contributing to advancements in cell signalling and kinase biology research.
- IUPAC
- 2-(5-Chloro-2-fluorophenyl)pteridin-4-yl]pyridin-4-yl-amine
ALK5 Kinase Inhibition
SD-208 functions as an inhibitor of ALK5 kinase. It has been employed in research settings to investigate the role of ALK5 in cellular processes, such as in bovine retinal vascular cells.
Cell Signaling Research
This compound aids in the study of cell signalling pathways. Its specific action on ALK5 kinase makes it a valuable tool for understanding TGF-β signalling and related biological events.
Tyrosine Kinase Biology
As a molecule interacting with tyrosine kinase-like pathways, SD-208 is used to explore the complex mechanisms regulated by these enzymes in various biological contexts.
| Molecular weight | 352.75 |
|---|---|
| Empirical formula | C17H10ClFN6 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | off-white to tan |
| Solubility | DMSO: >5 mg/mL |
| Storage temperature | 2-8°C |
| Application | SD-208 was used to inhibit the activity of ALK5 kinase in bovine retinal vascular cells.2 |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SD-208 used for?
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SD-208 is used to inhibit ALK5 kinase activity in cellular research, contributing to studies in cell biology, cell signalling, and kinase biology.
What are the CAS number and molecular formula for SD-208?
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The CAS number for SD-208 is 627536-09-8. The molecular formula is C17H10ClFN6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SD-208 with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
How should SD-208 be handled safely?
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SD-208 is classified with a GHS07 symbol and a Warning signal word, with hazard statement H302. Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.
How is SD-208 packed, shipped, and exported?
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SD-208 is typically supplied as a powder and stored at 2-8°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote for SD-208?
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To request a sample or quote for SD-208, please contact our sales team via the website or by phone.
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