SCH-28080
SCH-28080 (CAS 76081-98-6), with the empirical formula C17H15N3O and a molecular weight of 277.32 g/mol, is a chemical compound primarily utilised in research settings. It functions as an inhibitor targeting specific ion pumps. Its documented application involves studies on the role of H+/K+-ATPase in developmental biology, specifically in the establishment of the left-right axis in zebrafish embryos. Supplied by TSS as a white to light tan solid.
- IUPAC
- 2-methyl-8-(phenylmethoxy)imidazo[1,2-a]pyridine-3-acetonitrile

H+/K+-ATPase Inhibition in Developmental Studies
SCH-28080 has been employed as a research tool to investigate the function of H+/K+-ATPase. Its application in treating zebrafish embryos aids in understanding the precise role this enzyme plays in the crucial process of establishing the left-right axis during embryonic development.
Ion Channel Research
As an inhibitor of ion pumps, SCH-28080 is relevant for research focused on ion channels and their physiological roles. It can be used to probe cellular mechanisms involving proton and potassium transport in various biological systems.
Cell Biology and Signaling Investigations
This compound serves as a valuable reagent for cell biology studies, particularly those investigating cell signaling pathways. Its specific inhibitory action allows researchers to dissect the impact of H+/K+-ATPase activity on cellular processes and responses.
| Molecular weight | 277.32 |
|---|---|
| Empirical formula | C17H15N3O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to light tan |
| Solubility | DMSO: soluble >10 mg/mLH2O: insoluble |
| Storage temperature | −20°C |
| Application | SCH-28080 was used to treat zebrafish embryos to study the role of H+/K+-ATPase in establishment of left-right axis during development.1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Compatibility | for use with ABI 7700 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SCH-28080 used for?
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SCH-28080 is used in research, particularly in developmental biology studies on zebrafish embryos to investigate the role of H+/K+-ATPase in axis establishment, and in cell biology and neuroscience research involving ion channels and pumps.
What is the CAS number and formula for SCH-28080?
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The CAS number for SCH-28080 is 76081-98-6, and its empirical formula is C17H15N3O.
What grade and purity does Tech Serve Solutions supply for SCH-28080?
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Tech Serve Solutions supplies SCH-28080 with an assay of ≥98% by HPLC. This product is intended for research purposes and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling requirements for SCH-28080?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used when handling SCH-28080. It is classified under WGK Germany 3.
How is SCH-28080 packed, shipped, and exported?
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SCH-28080 is typically supplied as a solid and stored at -20°C. As a global supplier, TSS adheres to all regulations for packing, shipping, and exporting chemicals worldwide.
How can I request a sample or quote for SCH-28080?
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You can request a sample or obtain a quote for SCH-28080 by contacting our sales team through the website or by calling us directly.
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