Sertraline hydrochloride
Sertraline hydrochloride (CAS: 79559-97-0), with the empirical formula C17H17NCl2 · HCl and a molecular weight of 342.69 g/mol, is a selective serotonin reuptake inhibitor (SSRI). It is supplied as a white crystalline powder. Sertraline hydrochloride is widely recognised for its applications in scientific research, particularly in neuroscience and cell biology studies investigating neurotransmission and receptor function.
- IUPAC
- (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride

Neuroscience Research
Sertraline hydrochloride is utilised in studies of neurotransmission, focusing on serotonin pathways. Its role in modulating serotonin levels makes it a valuable tool for understanding neuronal signaling and brain function.
Glucocorticoid Receptor Studies
The compound has been employed in assays to investigate the impact of antidepressants on glucocorticoid receptor function in human research. This application aids in understanding the complex interplay between mood regulation and hormonal pathways.
Cell Signaling Investigations
As a bioactive small molecule, sertraline hydrochloride serves as a research agent in cell biology to probe signaling pathways. Its interaction with specific receptors allows for detailed examination of cellular responses.
| Molecular weight | 342.69 |
|---|---|
| Empirical formula | C17H17NCl2 · HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | DMSO: >20 mg/mL |
| Application | The effect of exposure of Sertraline hydrochloride was studied in chronically prepared ovine fetus.8 It was used in glucocorticoid function assay to study the effect of antidepressants on glucocorticoid receptor function in humans.9 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sertraline hydrochloride used for?
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Sertraline hydrochloride is used in scientific research, primarily in neuroscience and cell biology, to study neurotransmission, serotonin pathways, and glucocorticoid receptor function. It is a valuable tool for investigating cellular signaling mechanisms.
What is the CAS number and formula for Sertraline hydrochloride?
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The CAS number for Sertraline hydrochloride is 79559-97-0 and its empirical formula is C17H17NCl2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sertraline hydrochloride with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety precautions for handling Sertraline hydrochloride?
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When handling Sertraline hydrochloride, ensure you use appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound is classified with WGK Germany 3.
How is Sertraline hydrochloride packed and shipped?
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Sertraline hydrochloride is supplied as a white powder. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote for Sertraline hydrochloride?
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To request a sample or quote for Sertraline hydrochloride, please contact our sales team through the website or direct enquiry methods.
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