Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt
Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt (CAS: 141923-40-2 free base) is a synthetic peptide analogue. With a molecular weight of 747.89 (free base basis) and linear formula C34H57N11O8 · x CF3COOH, this compound serves as a selective activating peptide for PAR-1 (Protease-Activated Receptor 1). It is primarily utilized in cell biology research, particularly in studies involving cell signaling, neuroscience, and immune system regulation.
- IUPAC
- PAR-1 (Protease-Activated Receptor) Selective Activating Peptide,PAR1-AP,SFLLRN-NH2
- Synonyms
- PAR-1 (Protease-Activated Receptor) Selective Activating PeptidePAR1-APSFLLRN-NH2
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PAR-1 Signaling Studies
This peptide acts as a selective activator for PAR-1, making it invaluable for investigating G protein-coupled receptor signaling pathways in various cell types. Researchers use it to probe downstream effects of PAR-1 activation, such as calcium mobilization and gene expression.
Neuroscience Research
Due to PAR-1's presence in the nervous system, this compound aids in studying its role in neuronal function, neuroinflammation, and potentially neurological disorders. Its selectivity allows for targeted investigation of PAR-1-mediated effects in neural tissues.
Immunomodulation Research
The peptide is employed to explore the influence of PAR-1 on immune cell function and blood components. It helps elucidate mechanisms of immune system regulation and inflammation processes involving this receptor.
| Molecular weight | 747.89 (free base basis) |
|---|---|
| Linear formula | C34H57N11O8 · x CF3COOH |
| Assay | ≥98% (HPLC) |
| Solubility | H2O: >2 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt used for?
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It is used as a selective activating peptide for PAR-1 (Protease-Activated Receptor 1) in cell biology research, including studies of cell signaling, neuroscience, and immune system regulation.
What are the CAS number and formula?
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The CAS number for the free base is 141923-40-2. The linear formula is C34H57N11O8 · x CF3COOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥98% (HPLC). It is a research-grade chemical and not represented as USP, BP, or EP.
How should this chemical be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter. Store at -20°C. It is classified with WGK Germany 3.
How is this product shipped?
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This product is typically shipped and exported under conditions suitable for maintaining its stability, often at -20°C.
How can I request a sample or quote?
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Please contact our sales team through the website or by phone to request a sample or obtain a quotation for Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt.
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