Salsalate
Salsalate (CAS: 552-94-3, C14H10O5) is a white to tan powder with a molecular weight of 258.23. This salicylic acid derivative functions primarily as an anti-inflammatory agent and has been utilized in research to investigate its effects on insulin resistance and hepatic steatosis. It is typically supplied with an assay of ≥98% (HPLC) and is stored at room temperature.
- IUPAC
- 2-(2-Hydroxybenzoyl)oxybenzoic acid,2-Hydroxybenzoic acid 2-carboxyphenyl ester,disalicylic acid,salicyloxysalicylic acid,salicylsalicylic acid
- Synonyms
- disalicylic acidsalicylsalicylic acidsalicyloxysalicylic acid2-(2-Hydroxybenzoyl)oxybenzoic acid2-Hydroxybenzoic acid 2-carboxyphenyl ester

Research into Insulin Resistance
Salsalate has been employed in studies to explore its impact on palmitate-induced insulin resistance in biological models, contributing to a better understanding of metabolic disorders.
Investigation of Hepatic Steatosis
The compound was utilized in research investigating its effects on hepatic steatosis, particularly in obese rat models, offering insights into liver health and disease.
Enzyme Inhibition Studies
As a cyclooxygenase inhibitor, Salsalate is a valuable tool in biochemical research for studying enzymatic pathways and developing new therapeutic agents.
| Molecular weight | 258.23 |
|---|---|
| Empirical formula | C14H10O5 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | DMSO: ≥15 mg/mL |
| Storage temperature | room temp |
| Application | Salsalate was used to study the effect on palmitate-induced insulin resistance1 and hepatic steatosis in obese rats.2 |


Hazard statements
- H302Harmful if swallowed
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-50 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Salsalate used for?
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Salsalate is primarily used in scientific research to study its effects on insulin resistance and hepatic steatosis. It also serves as a tool in enzyme inhibition studies, particularly related to cyclooxygenase.
What is the CAS number and formula for Salsalate?
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Salsalate has the CAS number 552-94-3 and the empirical formula C14H10O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Salsalate with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade. This product is suitable for research and laboratory use.
How should Salsalate be handled and stored?
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Salsalate is classified as a GHS07 and GHS09 substance with a warning signal word. It is harmful if swallowed (H302) and very toxic to aquatic life (H400). Handle with appropriate personal protective equipment, avoid release to the environment (P273), and store at room temperature.
How is Salsalate shipped and exported?
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Salsalate is shipped and exported according to international regulations, including UN 3077 9 / PGIII for transportation. Please contact us for specific shipping and export details.
How can I request a quote or sample for Salsalate?
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To request a quote or a sample of Salsalate, please contact the Tech Serve Solutions sales team through our website or by phone.
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