Salermide

CAS 1105698-15-4C26H22N2O2Cell Biology

Salermide (CAS: 1105698-15-4) is a chemical compound with the molecular formula C26H22N2O2 and a molecular weight of 394.47 g/mol. This yellow powder is primarily utilised in biological research, particularly in cell biology and neuroscience studies. Its applications often involve investigating gene regulation and expression pathways, as well as understanding cellular signalling mechanisms.

IUPAC: N-{3-[(2-Hydroxy-naphthalen-1-ylmethylene)-amino]-phenyl}-2-phenyl-propionamide

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Salermide (C26H22N2O2) — chemical structure, CAS 1105698-15-4; Life Science, fine chemical supplied by Tech Serve Solutions

Cell Biology

01 /Applications

SIRT1 Inhibition Studies

Salermide has been employed in research settings to inhibit SIRT1 activity. For instance, it was used to treat human pulmonary artery smooth muscle cells to assess the impact of SIRT1 inhibition on atrogin expression via qPCR.

Cellular Signalling Research

The compound is valuable in exploring cellular signalling pathways. Its use in research contributes to a deeper understanding of the molecular mechanisms underlying various biological processes.

Gene Regulation and Expression Analysis

Salermide finds application in studies focused on gene regulation and expression. Researchers utilise it to investigate how cellular functions are controlled at the transcriptional level.

02 /Properties

Molecular weight	394.47
Empirical formula	C26H22N2O2
Assay	≥98% (HPLC)
Form	powder, yellow
Solubility	DMSO: >10 mg/mL
Storage temperature	2-8°C
Application	Salermide was used to treat human pulmonary artery smooth muscle cells to study the effect of SIRT1 inhibition on expression of atrogin by qPCR.1

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H317May cause an allergic skin reaction
H412Harmful to aquatic life with long-lasting effects

Precautionary statements

P273Avoid release to the environment
P280Wear protective gloves, clothing and eye/face protection

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	43-52/53
Safety statements (S)	36/37-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1105698-15-4

05 /Additional specifications

Storage Condition	desiccated

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Salermide used for?

Salermide is used in scientific research, particularly in cell biology, neuroscience, and studies concerning gene regulation and expression. It has been used to inhibit SIRT1 and study its effects on gene expression.

What are the CAS number and formula for Salermide?

The CAS number for Salermide is 1105698-15-4, and its molecular formula is C26H22N2O2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Salermide with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or pharmaceutical grade.

How should Salermide be handled and stored?

Salermide is classified as a Warning with hazard statements H317 (May cause an allergic skin reaction) and H412 (Harmful to aquatic life with long lasting effects). It should be stored at 2-8°C in a desiccated state. Handle with appropriate personal protective equipment to avoid skin contact. Disposal should be in accordance with environmental regulations.