Sal003
Sal003 (CAS: 1164470-53-4), a chemical compound with the formula C18H15Cl4N3OS and a molecular weight of 463.21 g/mol, is supplied by Tech Serve Solutions as a white to off-white powder. This bioactive small molecule is primarily utilised in cell biology research, specifically within the realms of cell signalling, neuroscience, and gene regulation. Its applications extend to studying RNA-protein translation inhibition, making it a valuable reagent for understanding complex biological pathways.
- IUPAC
- (2E)-3-Phenyl-N-[2,2,2-trichloro-1-[[[(4-chlorophenyl)amino]thioxomethyl]amino]ethyl]-2-propenamide,3-Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide

Investigating eIF2α in Apoptosis Pathways
Sal003 has been employed as a research tool to investigate the role of eukaryotic initiation factor 2 alpha (eIF2α) in Subtilase cytotoxin-induced apoptosis within HeLa cell models. This application aids in understanding cellular defence mechanisms against toxic insults.
Cell Biology Research
As a bioactive small molecule, Sal003 is suitable for various cell biology studies. It can be used to probe cellular processes, including cell signalling, gene expression regulation, and the mechanisms of RNA-protein translation.
Neuroscience and Related Signaling Studies
Its classification under Cell Signaling and Neuroscience suggests potential applications in research related to neuronal function and signalling pathways relevant to neurological processes.
| Molecular weight | 463.21 |
|---|---|
| Empirical formula | C18H15Cl4N3OS |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | DMSO: ≥10 mg/mL |
| Storage temperature | 2-8°C |
| Application | Sal003 was used to study the role of eIF2α in Subtilase cytotoxin-induced apoptosis in HeLa cells.1 |

Hazard statements
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P501Dispose of contents and container per local regulations
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Compatibility | for use with Bio-Rad CFX96 |
|---|---|
| Storage Condition | desiccatedprotect from light |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sal003 used for?
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Sal003 is used in scientific research, particularly in cell biology, cell signalling, neuroscience, and gene regulation studies. It has been specifically utilized to investigate the role of eIF2α in Subtilase cytotoxin-induced apoptosis in HeLa cells and as an RNA-protein translation inhibitor.
What are the CAS number and chemical formula for Sal003?
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The CAS number for Sal003 is 1164470-53-4, and its chemical formula is C18H15Cl4N3OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sal003 with a purity of ≥98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling precautions for Sal003?
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Sal003 is classified under GHS09 with the signal word 'Warning' and carries the hazard statement H410 (Very toxic to aquatic life with long lasting effects). Handling should be done with appropriate personal protective equipment, and it should be stored desiccated and protected from light at 2-8°C. Avoid release into the environment.
How is Sal003 packed and exported?
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Sal003 is typically supplied as a powder and is packaged to maintain its integrity during transport. Tech Serve Solutions is a global supplier and exporter of fine chemicals.
How can I request a sample or quote for Sal003?
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To request a sample or a quotation for Sal003, please contact the Tech Serve Solutions sales team through our website or by phone. Please reference the product name and CAS number.
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